Drug Delivery Technologies

NCBiotech Company Directory is a comprehensive listing of North Carolina's life science industry New search

Company Title Company Description City
Achelios Therapeutics Inc.

Achelios Therapeutics develops novel topical therapeutics for the treatment of inflammatory pain, including migraine and temporomandibular joint disorder pain.

Durham
Adámas Nanotechnologies Inc.

Adámas Nanotechnologies develops and produces fluorescent nanodiamond particles for life science, medical and industrial applications, including life science research, drug delivery, bioimaging, anti-counterfeiting, oil additives and cosmetics.

Raleigh
Adroit Pharmaceutical Development LLC

Adroit Pharmaceutical Development identifies new and improved formulations and process technologies. Its primary focus is on inhalation and dermatological product development.

Durham
Advanced Chemotherapy Technologies Inc.

Advanced Chemotherapy Technologies, a UNC startup, has developed a novel device for infusing chemotherapies directly into poorly-vascularized pancreatic tumors.

Raleigh
Aerie Pharmaceuticals Inc.

Aerie Pharmaceuticals discovers, develops and commercializes first-in-class therapies for the treatment of patients with glaucoma.

Durham
Aestas Pharma Inc.

Asetas Pharma develops novel diagnostic imaging and disease-modifying therapeutic agents to enable the early treatment and reversal of Alzheimer’s and Parkinson’s disease when clinical signs are not yet pronounced.

Lewisville
Affinergy LLC

Affinergy develops peptide-based technologies, including diagnostic products, research tools and therapeutic drug monitoring products for use by clinicians and researchers.

Morrisville
Alpha Nano Tech LLC

Alpha Nano Tech provides nanoparticle and exosome characterization services.

Research Triangle Park
AnelleO

AnelleO is developing a 3D printed intravaginal ring that can be used as a platform for treating a wide range of women's health conditions.

Chapel Hill
Apeirolux Pharmaceutical Inc.

Apeirolux Pharmaceutical is developing a tumor-cell selective topical skin cream for the treatment of skin cancer.

Fuquay Varina
Applied LifeSciences & Systems Poultry Inc.

Applied LifeSciences & Systems Poultry develops automated bio-system solutions for detecting, targeting and delivering vaccines to poultry. ALS-S technology aims to reduce the need for antibiotics by improving vaccination delivery.

Raleigh
Arcato Laboratories Inc.

Arcato Laboratories develops specialty oral healthcare products. Its first product is a sustained-release medicated wax that treats oral discomfort caused by orthodontic appliances.

Durham
Ardeal Pharma Inc.

Ardeal Pharma is a virtual pharma company developing patented stabilized sulforaphane for the dermal pharmaceutical and cosmetic markets.

Brevard
Ardeal Research Institute

Ardeal Research Institute is a non-profit organization that develops drug discovery capabilities of the natural resources in Western North Carolina. The Institute has collaboration agreements in place with Brevard College and the N.C. Arboretum.

Brevard
Avior Inc.

Avior Bio is an developing a nanoparticle-based drug delivery technology to deliver lipophilic drugs with high bioavailability. It is testing its technology using a molecule for the treatment of pruritus in chronic kidney disease.

Holly Springs
Aweve LLC

Aweve designs and manufactures cosmeceuticals that utilize nanoparticles for the delivery of retinol, ascorbic acid and kojic acid to address wrinkles, lines, age spots and elasticity in skin.

Raleigh
Banner Life Sciences LLC

Banner Life Sciences develops formulation technologies (gelcaps, tablets and sterile injectables) and licenses and markets prescription, over-the-counter and nutritional products.

High Point
BD Technologies and Innovation

BD Technologies and Innovation develops technologies for parenteral drug delivery, advanced diagnostics, smart medical devices, genomic research and supports external innovation. The RTP site is BD's corporate technology R&D and innovation center.

Research Triangle Park
Bent Creek Institute Inc.

Bent Creek Institute is a 501(c)3 non-profit botanical research and economic development organization serving primarily North Carolina-based natural products companies seeking to innovate botanical wellness solutions.

Asheville
BioCytics Inc.

BioCytics researches and develops personalized cellular immunotherapy cancer therapies with the latest technology and equipment. BioCytics also offers contract R&D, and is incubated within the Carolina BioOncology Institute.

Huntersville
BioDelivery Sciences International Inc.

BioDelivery Sciences is a specialty pharmaceutical company with a focus in the areas of pain management and addiction. The company's lead products utilize a buccal film delivery system.

Raleigh
BioLink Life Sciences Inc.

BioLink provides contract product development support through custom synthesis and testing.

Cary
BioMarck Pharmaceuticals Ltd.

BioMarck develops drugs to treat pulmonary diseases and disorders, such as chronic obstructive pulmonary disease, ARDS, cystic fibrosis and lung cancer.

Durham
Capture Pharmaceuticals Inc.

Capture Pharmaceuticals develops oral treatments for removing toxic or radioactive metals in contaminated individuals.

Chapel Hill
Catalent Pharma Solutions LLC

Catalent provides drug development and manufacturing services for the pharma, biotech and consumer sectors. Core offerings include biologics, parenterals, oral solids, softgel, inhalation, clinical supply services and analytical services.

Morrisville
Charles River Laboratories (Morrisville)

Charles River Laboratories' Oncology Center of Excellence provides in vivo and in vitro oncology and immuno-oncology research services.

Morrisville
Chesson Laboratory Associates Inc.

Chesson Labs develops prescription and over-the-counter polymer-based medical products for wound care and skin and nail care products.

Durham
Chimerix Inc.

Chimerix discovers, develops and commercializes broad spectrum antivirals for the prevention and treatment of life-threatening viral infections.

Durham
CiVentiChem

CiVentiChem provides contract development and manufacturing services. Services include cGMP manufacturing of APIs, GMP analytical services, process development, medicinal chemistry and custom synthesis.

Cary
Cloud Pharmaceuticals Inc.

Cloud Pharmaceuticals designs and develops novel drug molecules using computational design for a wide range of therapeutic areas including cancer, inflammation, CNS disorders and rare diseases.

Research Triangle Park
Cognosci Inc.

Cognosci develops neurorestorative therapies for Alzheimer's disease, multiple sclerosis, traumatic brain injury, nerve crush and other disease and trauma indications.

Durham
Concentrx Pharmaceuticals Inc.

Concentrx develops inhaled prescription products for asthma and COPD, including a unit dose disposable dry powder inhaler.

Durham
Daily Manufacturing Inc.

Daily Manufacturing manufactures vitamins, minerals and herbals. The company also manufactures products for other supplement companies with their own brand names.

Rockwell
DaVINCI Biomedical Research Products Inc.

DaVINCI Biomedical Research is an AAALAC-accredited contract lab that performs GLP and non-GLP preclinical animal studies. DaVINCI specializes in regenerative medicine, cardiovascular, orthopedic and medical device applications.

Garner
Dharma Laboratories LLC

Dharma Laboratories develops dosage forms, including oral solids, liquids, injectables, topicals and specialty products.

Morrisville
Dignify Therapeutics LLC

Dignify Therapeutics develops bladder and bowel drug therapies for spinal cord-injured, multiple sclerosis and similar patient populations with voiding dysfunction.

Research Triangle Park
Dualogics LLC

Dualogics researches and develops bispecific antibody products based on their proprietary OrthoMab platform.

Chapel Hill
EG-GILERO

EG-GILERO provides design, development and manufacturing services within the medical devices, drug delivery and primary pharmaceutical packaging markets.

Morrisville
EnDev Laboratories

EnDev Labs, a wholly owned subsidiary of Tergus Pharma, offers topical research and development, formulation, process development, analytical development and regulatory services for therapeutic skin care and prescription dermatological products.

Kannapolis
Entegrion Inc.

Entegrion develops biologic and medical device technologies to enhance the safety and availability of the human blood supply. The company also provides blood supply-related contract R&D services to the U.S. Department of Defense.

Durham
Exodos Life Science Partners

Exodos Life Sciences advances product concepts through the 505(b)(2) process to early clinical proof-of-principle and sale. Exodus specializes in topical formulations for the treatment of pain and inflammation, cold sores and nail fungis.

Chapel Hill
Falcon Therapeutics Inc.

Falcon Therapeutics is developing personalized neural stem cell therapies to treat cancers.

Durham
Fresenius Kabi USA LLC

Fresenius Kabi manufactures medical devices and sterile injection- and infusion-based drug-delivery products.

Wilson
Genebiology Inc.

GeneBiology identifies, patents and develops new parenteral formulations of approved drugs for unmet medical needs using the 505b2 regulatory pathway.

Research Triangle Park
Genencine Therapeutics LLC

Genencine Therapeutics develops mRNA vaccines for the prevention and treatment of cancer, viral diseases and autoimmune diseases, as well as mRNA therapeutic drugs for genetic diseases.

Durham
Glenmark Pharmaceuticals Inc., USA

Glenmark Pharmaceuticals discovers small-molecule drugs and biologics in the areas of oncology, respiratory disease and dermatology, and manufactures and distributes APIs and generics. The Monroe site manufactures oral solids, injectables and topicals.

Monroe
Gyrus Pharmaceuticals Inc.

Gyrus Pharmaceuticals is developing treatments for serious diseases of the central nervous system using proprietary therapeutic agents and nanoparticles for noninvasive delivery to the CNS.

Chapel Hill
Hammock Pharmaceuticals Inc.

Hammock Pharmaceuticals licenses and develops women's health and urology products. It is developing a metronidazole and clindamycin vaginal gel for the treatment of bacterial vaginosis, and a urology product for the treatment of radiation cystitis.

Charlotte
HDH Pharma Inc.

HDH Pharma offers contract chemistry research services to the biopharma industry, including medicinal and process chemistry; organic synthesis; CMC analytical and bioanalytical services; and API intermediate, inhibitor and screening compound provision.

Morrisville
High Point Clinical Trials Center

High Point Clinical Trials Center conducts phase one and two clinical research studies to test emerging drugs for pharmaceutical companies.

High Point
IMMvention Therapeutix Inc.

IMMvention Therapeutix develops a platform technology that modulates innate immunity to treat unmet medical needs in cancer, autoimmune/inflammatory and infectious diseases.

Durham
Indicus Pharma LLC

Indicus develops generic formulations in oral solid dosage forms, parenterals and ophthalmics. Products are manufactured at a partner facility in India.

Raleigh
Inhalon Biopharma Inc.

Inhalon Biopharma is developing monoclonal antibodies (mAb) using technology that enables trapping of pathogens in mucus secretions for treating diseases of the respiratory tract.

Carrboro
Initos Pharmaceuticals LLC

Initos Pharmaceuticals is developing a platform delivery technology for nucleic acid therapeutics to develop agents to enhance intracellular delivery of oligonucleotides, peptides and proteins.

Chapel Hill
Intarcia Therapeutics Inc.

Intarcia Therapeutics is developing a continuous subcutaneous delivery system for the treatment of Type 2 diabetes. The RTP location discovers and develops peptide therapeutic drugs to augment Intarcia's drug delivery platform.

Research Triangle Park
Knightpoint Group LLC

Knightpoint Group offers contract development and manufacturing services, specializing in parenteral and respiratory drug delivery products. Knightpoint Group is also developing a platform autoinjector technology to deliver emergency drugs.

Cary
Lindy Biosciences Inc.

Lindy Biosciences develops protein therapeutic formulations for non-standard formulations such as suspension formulations (for high-concentration delivery of antibodies), encapsulation (for sustained/controlled release) or dry powder pulmonary delivery.

Research Triangle Park
Liquidia Technologies Inc.

Liquidia Technologies develops and commercializes human therapeutics for the treatment of pulmonary arterial hypertension and post-operative pain using its proprietary particle engineering technology.

Morrisville
Locus Biosciences Inc.

Locus Biosciences is developing CRISPR-engineered bacteriophage (“crPhage”) products that kill target bacteria by irreversibly destroying their DNA while leaving the many species of beneficial bacteria in the body unharmed.

Morrisville
Lonza RTP

Lonza provides bioscience products and services ranging from cell culture and discovery technologies for research to quality control tests and software that ensures product quality. Its RTP site produces hepatocytes for use in drug research.

Morrisville
Mayne Pharma USA

Mayne Pharma manufactures oral and topical dosage branded and generic pharmaceuticals. Mayne Pharma also provides contract development and manufacturing services. Mayne Pharma's U.S. headquarters is in Raleigh.

Raleigh
Mayne Pharma USA (Greenville)

Mayne Pharma manufactures branded and generic oral solid dose pharmaceuticals. The Greenville site is Mayne Pharma’s U.S. development and manufacturing facility.

Greenville
MedKoo Biosciences Inc.

MedKoo supplies anticancer small molecule chemical reagents and kinase inhibitor for oncology research. MedKoo also offers drug discovery research services to the pharmaceutical industry, medical research organizations and academic institutions.

Morrisville
Micell Technologies Inc.

Micell Technologies develops combination-product therapies for interventional cardiology. Micell markets MiStent, a drug-eluting stent, in Europe and certain other regions.

Durham
Micropore Technologies Inc.

Micropore Technologies provides particle emulsification and encapsulation equipment, manufacturing and consulting for industries including pharmaceuticals, nutraceuticals, agrochemicals and animal feed.

Morrisville
Midatech Pharma US Inc.

Midatech Pharma US develops and commercializes oncology treatments and supportive care.

Raleigh
Mucodel Pharma LLC

Mucodel Pharma develops technologies for enhancing drug delivery via mucosal routes of administration. Its first candidate is a buccal gel for emergency treatment of opioid overdose.

Greensboro
Mucommune LLC

Mucommune researches improved protection against infectious diseases transmitted at mucosal surfaces. Mucommune's current focus is a method to prevent sexually transmitted infections using monoclonal antibodies encapsulated in a polymeric capsule.

Carrboro
Nexgen Biosciences

Nexgen is developing next-generation anti-infective therapeutics effective against antibiotic-resistant strains of micro-organisms.

Raleigh
Nitta Gelatin NA Inc.

Nitta Gelatin manufactures food, pharmaceutical and technical gelatin, and is the maker of beMatrix Low Endotoxin Gelatin. beMatrix is used in the fields of regenerative medicine, medical devices and scientific research.

Morrisville
Novex Innovations LLC

Novex Innovations is a contract development and manufacturing organization (CDMO) supporting small and startup life science companies in the development of their products, from concept through manufacturing and commercialization.

Winston-Salem
Nu Chemie LLC

NuChemie is developing and commercializing nanomaterials for drug delivery and water soluble and traceable bioconjugation reagents. NuChemie also provides custom synthesis services.

Charlotte
OncoTrap Inc.

OncoTrap is developing a nucleic acid delivery platform for accommodating nucleic acid-based therapeutics, designed to deliver therapeutic genes to tumor sites.

Chapel Hill
Oriel Therapeutics Inc., a Sandoz company (Durham)

Oriel operates as Sandoz' product development center, which develops respiratory products as generic alternatives to patented drugs for asthma and COPD. It also develops and commercializes pre-metered unit and multi-dose dry powder delivery systems.

Durham
Osmotica Pharmaceutical Corp.

Osmotica Pharmaceutical specializes in drug-delivery technologies and neurology-based therapies, including a treatment for Parkinson's disease.

Wilmington
Parion Sciences Inc.

Parion Sciences develops therapies to treat defects of the innate mucosal defense system in respiratory and ophthalmology diseases.

Durham
Path BioAnalytics Inc.

Path BioAnalytics develops rheological assays for testing trans-mucosal drug delivery systems, mucolytic compounds, inhaled medications for respiratory diseases, antimicrobials and treatments for diseases that impact the body's mucosal layers.

Chapel Hill
Piedmont Animal Health LLC

Piedmont Animal Health develops, licenses and markets animal health therapeutics with a focus on major companion animal categories.

Greensboro
Plakous Therapeutics LLC

Plakous Therapeutics is developing biotherapeutics from post-delivery placenta to promote regenerative healing for diseases including osteoarthritis, necrotizing enterocolitis, wound healing and tissue engraftment.

Winston-Salem
Polyzen Inc.

Polyzen is a contract manufacturer that designs, develops, and manufactures polymer-based medical devices. Polyzen has polymer processing capabilities for prototyping and volume production.

Apex
Precision BioSciences Inc.

Precision BioSciences utilizes a proprietary genome editing method called ARCUS to treat cancers and genetic diseases, and enable the development of safer, more productive food sources.

Durham
Recipharm Laboratories Inc.

Recipharm in RTP provides contract inhalation, injectable and semi-solid product development. Services include formulation development, analytical and stability testing, scale-up and tech transfer, and cGMP manufacturing for clinical trial material.

Morrisville
Retroject Inc.

Retroject is developing a device to deliver glaucoma drugs to targeted sites in the eye.

Chapel Hill
Rilento Pharma LLC

Rilento Pharma is an early stage drug delivery company developing non-addictive oral surgery pain management technologies that are synchronized with the biologic process of wound healing.

Raleigh
RTI International

RTI, an independent, nonprofit institute, offers scientific and technical expertise in social and laboratory sciences, engineering and international development to government and commercial clients worldwide.

Research Triangle Park
Sagent Pharmaceuticals

Sagent Pharmaceuticals develops, manufactures, packages and markets pharmaceutical products with an emphasis on injectables. Its Raleigh site produces sterile injectables and lyophilized formulations of biosimilars.

Raleigh
Satsuma Pharmaceuticals Inc.

Satsuma Pharmaceuticals is developing best-in-class intranasal drug products to address the significant unmet medical needs of acute migraine sufferers.

Research Triangle Park
SciKon Innovation Inc.

SciKon creates life science products that replicate the performance of human organ systems using benchtop microfluidic devices. Products simulate pharmacokinetics to evaluate human responses to toxicants and drugs (exposure, metabolism, bioactivation).

Research Triangle Park
Shoaf Scientific Consultants Inc.

Shoaf Scientific Consultants provides research and development services in plant redox bioenergetics, antimicrobial surface technologies and molecular photochemical studies in singlet oxygen and superoxide-free radical anion as applied to aging.

Lexington
SiNON Therapeutics

SiNON is developing technology to treat neurological diseases by increasing the ability of drugs to cross the Blood Brain Barrier (BBB).

Research Triangle Park
Symmetry Biosciences Inc.

Symmetry Biosciences provides contract research, specialized chemistry services and bioanalytic services to the biotech, pharmaceutical, medical device, agrochemical and fine chemical industries.

Raleigh
Textile-Based Delivery Inc.

Textile-Based Delivery develops and manufactures fabrics that integrate controlled release matrices, offering topical and transdermal dosing of active ingredients.

Conover
Thrudermic LLC

Thrudermic develops a transdermal nanotechnology for the formulation and delivery of dosable bio-cannabis products.

Wilmington
United Therapeutics Corp.

United Therapeutics develops and commercializes products to treat cardiopulmonary diseases, infectious diseases and cancer.

Research Triangle Park
VivImmune LLC

VivImmune is developing a chitosan-based delivery system for the local, sustained delivery of recombinant cytokines therapeutics to treat cancers.

Cary
Wake Forest Innovations

Wake Forest Innovations improves health through collaborative innovation between industry and Wake Forest Baptist Medical Center faculty and staff. Wake Forest Innovations manages technology for license, and offers preclinical and core lab services.

Winston-Salem
Wilmington Pharmaceuticals LLC

Wilmington Pharmaceuticals develops fast-dissolving dosage forms for established medicines.

Wilmington
Xollent Biotech Inc.

Xollent Biotech is developing a therapeutic to treat cardiovascular disease based on exosome-secreting cells.

Cary
Yukon Medical LLC

Yukon Medical designs and manufactures pharmaceutical drug preparation and delivery devices, including vial access devices, valves and drug reconstitution systems.

Raleigh
Zenomics Inc.

Zenomics is developing a microneedle transdermal patch technology for diabetes, which is able to sense blood glucose levels and respond with appropriate concentrations of insulin.

Durham

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