Toxicology and Pharmacology Tools

NCBiotech Company Directory is a comprehensive listing of North Carolina's life science industry New search

Company Title Company Description City
Integrated Nonclinical Development Solutions Inc.

INDS offers nonclinical drug development support, including pharmacology, toxicology, pharmacokinetics and regulatory services.

Durham
Invitrox Inc.

Invitrox provides GLP-compliant bioanalytical services for nonclinical and clinical drug development studies, with expertise in method development and validation, small and large molecules, sample analysis, metabolites, biomarkers and drug monitoring.

Research Triangle Park
Aerie Pharmaceuticals Inc.

Aerie Pharmaceuticals discovers, develops and commercializes first-in-class therapies for the treatment of patients with glaucoma.

Durham
Aestas Pharma Inc.

Asetas Pharma develops novel diagnostic imaging and disease-modifying therapeutic agents to enable the early treatment and reversal of Alzheimer’s and Parkinson’s disease when clinical signs are not yet pronounced.

Lewisville
Affinergy LLC

Affinergy develops peptide-based technologies, including diagnostic products, research tools and therapeutic drug monitoring products for use by clinicians and researchers.

Morrisville
Alera Labs LLC

Alera Labs provides contract research analytical chemistry, in vitro toxicology, GLP analysis and preformulation services to pharmaceutical, biotech and medical device companies.

Durham
Altis BioSystems Inc.

Altis Biosystems has developed a stem cell technology that recreates the human intestinal epithelium in a 2D or 3D layer of intestinal stem and differentiated cells, which can be used for compound screening, microbiome research and disease modeling.

Chapel Hill
Antech Diagnostics Inc.

Antech Diagnostics provides clinical and veterinary hematology analysis, clinical chemistry, urinalysis and coagulation testing.

Morrisville
Appealing Products Inc.

Appealing Products develops products for forensics and personal protection from toxic materials such as inorganics, gases and poisons in foods, animal feeds and liquids.

Raleigh
ArrayXpress Inc.

ArrayXpress applies bioinformatics to optimize bioprocesses, increase diagnostic efficiency and provide contract research services, focusing on next generation genomics.

Raleigh
Atlas Regeneration Inc.

Atlas Regeneration develops bioinformatics platforms for drug discovery related to regenerative medicine and stem cell research. Atlas Regeneration also screens drugs in silico for drug repositioning.

Winston-Salem
Attagene Inc.

Attagene has developed a pathway profiling technology to evaluate the impact of pharmaceuticals and environmental chemicals on over 100 transcription factors and 48 nuclear receptors.

Morrisville
Barbaresco Pharma LLC

Barbaresco Pharmaceuticals is a target drug discovery company focused on obesity, cardiovascular and metabolic diseases.

Chapel Hill
BioAgilytix Labs Inc.

BioAgilytix is a bioanalytical lab specializing in large-molecule bioanalysis, offering PK, immunogenicity, biomarkers and cell-based assays in support of the development and release testing of biologics and small-molecule therapeutics.

Durham
BioIVT

BioIVT provides biological specimens, specializing in control and disease state human and animal tissues. This site develops and commercializes cell-based drug toxicity-testing products for pharmaceutical development, based on hepatocyte technologies.

Durham
BioRxn LLC

BioRxn develops NMR-based metabolomic technology, including bioreactor and artificial liver systems, for non-invasive monitoring of metabolic biomarkers. BioRxn also provides conventional metabolomic services.

Chapel Hill
Boragen Inc.

Boragen is developing a synthetic chemistry platform that leverages the unique characteristics of boron to address life science needs in crop protection and animal health.

Research Triangle Park
Brite Bio Inc.

Brite Bio provides contract research services, including cell culture services, cell-based assays, biomarker assay development, toxicological assays, bio-banking, drug target identification and gene expression profiling and characterization.

Research Triangle Park
Burleson Research Technologies Inc.

Burleson Research Technologies provides laboratory services to the biotechnology, pharmaceutical, chemical manufacturing and health care industries with proof-of-concept, preclinical, clinical and toxicology studies.

Morrisville
Calvert Laboratories Inc.

Calvert Labs provides preclinical research and contract drug discovery and development services, such as lead identification and lead optimization services.

Cary
Celldom Inc.

Celldom is developing next generation, high throughput single cell analysis technology with applications in research, drug discovery and drug development. Its technology enables the investigation of diversity in large cell populations.

Durham
Charles River Laboratories (Hillsborough)

Charles River Laboratories' Hillsborough location provides contract toxicologic pathology and histology services.

Hillsborough
Charles River Laboratories Inc. - Pathology Associates

Charles River Laboratories - Pathology Associates provides pathology and toxicology contract services.

Durham
ChemoGenics Biopharma LLC

ChemoGenics BioPharma provides collaborative drug discovery, bioanalytical, formulation and scale-up services. Capabilities include medicinal chemistry, DMPK, bioinformatics and preclinical models in cancer, inflammation and metabolic diseases.

Research Triangle Park
ChemQ Bioscience LLC

ChemQ Bioscience develops and markets novel liquid products, such as bio-preservation media, tissue perfusion solutions and liquid-based cytology processing kits.

Research Triangle Park
Creative Scientist Inc.

Creative Scientist provides in bioassay development, primary cell isolation and pre-clinical contract research. Testing offered includes cytotoxicity, cell viability, proliferation, anti-angiogenesis, endotoxin (LPS), nitric oxide, nitrate and nitrite.

Research Triangle Park
Daily Manufacturing Inc.

Daily Manufacturing manufactures vitamins, minerals and herbals. The company also manufactures products for other supplement companies with their own brand names.

Rockwell
Drug Disposition Associates LLC

Drug Disposition Associates provides ADME science and drug development consulting services.

Chapel Hill
Drumetix Laboratories LLC

Drumetix provides bioanalytical support for drug metabolism, pharamacokinetics and toxicokinetic (DMPK, ADME) studies, as well as LC-MS/MS analysis of small-molecule biomarkers, such as neurotransmitters, all-trans retinoic acid and creatinine.

Greensboro
Enzerna Biosciences Inc.

Enzerna Biosciences is developing molecular tools for reversible, precise manipulation of gene expression, using technologies that create sequence-specific RNA binding proteins. Enzerna also offers mitochondrial toxicity models and testing.

Raleigh
EPL Inc.

EPL provides GLP-compliant toxicologic pathology and related services including necropsy, histology, immunohistochemistry, pathology evaluation, EM, stereology, pathology peer reviews, specimen storage and consultation.

Durham
Eurofins Agroscience Services LLC

Eurofins Agroscience Services provides contract research services, product development consulting and technical support to the crop protection, agricultural biotechnology and pest control industries.

Mebane
First Flight Biosciences Inc.

First Flight Biosciences provides contract drug discovery research services, including lead optimization in preclinical drug discovery, assay development, compound profiling, high-throughput screening, in vivo pharmacology, DMPK and bioanalytics.

Cary
GEM Tox Labs

GEM Tox Labs conducts research focused on cancer biotechnology, food safety and toxicology, with a special emphasis on cancer biomarker discovery and validation.

Greenville
Genebiology Inc.

GeneBiology identifies, patents and develops new parenteral formulations of approved drugs for unmet medical needs using the 505b2 regulatory pathway.

Research Triangle Park
Howard Associates LLC

Howard Associates offers preclinical contract research to the pharma industry, primarily on rodent models to predict the efficacy of experimental compounds for CNS diseases and to predict side effects. The company also offers science editing and writing.

Research Triangle Park
Icagen Inc.

Icagen partners with global pharmaceutical and biotech companies to generate high-quality, advanced leads, with expertise in kinases, GPCR’s, ion channels and transporters.

Durham
Immuno-Safety Consulting LLC

Immuno-Safety Consulting provides immunotoxicology consulting services, including non-clinical and clinical testing strategies for immunomodulatory drugs.

Chapel Hill
Integrated Laboratory Systems Inc.

ILS provides GLP toxicology, histopathology, molecular biology and research and development services to government and commercial clients in agro-chemical, biopharmaceutical and environmental industries.

Morrisville
Lonza RTP

Lonza provides bioscience products and services ranging from cell culture and discovery technologies for research to quality control tests and software that ensures product quality. Its RTP site produces hepatocytes for use in drug research.

Morrisville
MEDTOX Diagnostics Inc.

MEDTOX Diagnostics manufactures and distributes instant drugs of abuse testing devices for use by the government, hospital and medical centers and workplace markets.

Burlington
MOLTOX

MOLTOX manufactures products used in mutagenicity testing and human risk assessment, as well as prepared bacteriological media including nutrient, selective and enrichment media used in industrial, environmental and molecular microbiology.

Boone
OpAns LLC

OpAns provides analytical services to support discovery, preclinical, toxicology and clinical studies.

Durham
Parion Sciences Inc.

Parion Sciences develops therapies to treat defects of the innate mucosal defense system in respiratory and ophthalmology diseases.

Durham
Pastoor Science Communications LLC

Pastoor Science Communications provides services and consultation in the areas of strategic legal support, technical expertise in toxicology and human health risk assessment, and science communication.

Greensboro
Powered Research LLC

Powered Research provides contract research services to life sciences companies using both established and novel nonclinical models.

Research Triangle Park
Rescindo Therapeutics Inc.

Rescindo Therapeutics discovers novel therapeutic targets and drugs for human genetic disorders based on humanized zebrafish in vivo modeling.

Durham
RTI International

RTI, an independent, nonprofit institute, offers scientific and technical expertise in social and laboratory sciences, engineering and international development to government and commercial clients worldwide.

Research Triangle Park
SciKon Innovation Inc.

SciKon creates life science products that replicate the performance of human organ systems using benchtop microfluidic devices. Products simulate pharmacokinetics to evaluate human responses to toxicants and drugs (exposure, metabolism, bioactivation).

Research Triangle Park
ScitoVation LLC

ScitoVation supports and advances research on the effects of chemical compounds on human health. ScitoVation works with clients to develop safer pharmaceuticals, food ingredients, agricultural chemicals, commodity chemicals and consumer products.

Durham
SeaTox Research Inc.

SeaTox Research develops bioassays for the detection of marine toxins and conducts pharmaceutical development through bioprospecting.

Wilmington
Shoaf Scientific Consultants Inc.

Shoaf Scientific Consultants provides research and development services in plant redox bioenergetics, antimicrobial surface technologies and molecular photochemical studies in singlet oxygen and superoxide-free radical anion as applied to aging.

Lexington
Smithers Viscient LLC

Smithers Viscient provides environmental testing and toxicology services for the pharmaceutical, veterinary, agriculture, chemical and personal-care industries. The company's lab in Snow Camp conducts avian and wildlife toxicology testing.

Snow Camp
SonoVol Inc.

SonoVol is developing preclinical imaging technology that can be applied to the animal models that researchers use to evaluate the efficacy and toxicity of new drugs before they enter clinical trials.

Durham
Statera Environmental Inc.

Statera develops innovative environmental monitoring products and provides environmental technology consulting services.

Raleigh
Syngenta Crop Protection LLC

Syngenta works to increase plant yield by developing products for disease, insect and weed control and drought tolerance. The Greensboro site is the largest site in North America and performs crop protection product development.

Greensboro
Tergus Pharma LLC

Tergus Pharma provides topical and semi-solid development, formulation, analysis and testing services, with expertise in IVRT method development. The company has cGMP manufacturing, phase one through four clinical supplies and logistics capabilities.

Durham
Thermo Fisher Scientific (Durham)

Thermo Fisher’s Pharma Services Division offers drug development and manufacturing. The Durham site provides contract development and manufacturing services for solid and sterile dosage forms, including small-molecule API and biologic drug substances.

Durham
Toxicology Services Inc.

Toxicology Services works with small and mid-sized pharmaceutical companies and CROs to plan, conduct and summarize toxicology studies, including safety pharmacology and PK/ADME studies.

Chapel Hill
Wake Forest Innovations

Wake Forest Innovations improves health through collaborative innovation between industry and Wake Forest Baptist Medical Center faculty and staff. Wake Forest Innovations manages technology for license, and offers preclinical and core lab services.

Winston-Salem
Xenobiotic Detection Systems International Inc.

Xenobiotic Detection Systems offers patented bioassays to facilitate assessment of environmental and human health risks.

Durham
Xyzagen Inc.

Xyzagen offers clinical pharmacology and nonclinical discovery consulting and contract research. Xyzagen's services include small-molecule bioanalysis, rodent pharmacokinetics, pharmacology, toxicokinetics and clinical phase 1 and 2 PK analysis.

Pittsboro
Zorbius Biopharma Inc.

Zorbius Biopharma provides analytical, formulation and nanotechnology-related services to pharmaceutical, biotech and medical device companies.

Morrisville