Digestive System and Gastrointestinal Diseases

NCBiotech Company Directory is a comprehensive listing of North Carolina's life science industry New search

Company Title Company Description City
ALP Life Sciences Inc.

ALP Life Sciences has formulated and markets a High-3 fish oil supplement to increase omega-3 absorption and bioavailability for the treatment of fatty liver disease and inflammatory diseases.

Black Mountain
Altis BioSystems Inc.

Altis Biosystems has developed a stem cell technology that recreates the human intestinal epithelium in a 2D or 3D layer of intestinal stem and differentiated cells, which can be used for compound screening, microbiome research and disease modeling.

Chapel Hill
Artizan Biosciences Inc.

Artizan is developing a platform for identifying and targeting pathogenic intestinal bacteria, with a focus on inflammatory bowel disease and potential applications in autoimmune diseases, obesity, skin, lung and central nervous system diseases.


CELLF-Bio is developing a novel regenerative medicine-based therapy for fecal incontinence.

CMP Pharma Inc.

CMP develops, manufactures and commercializes specialty pharmaceuticals, focused on niche liquid and topical products that solve unmet patient needs.

Cook Medical

Cook Medical develops and manufactures devices used in gastrointestinal endoscopy to diagnose and treat esophageal, gastric, pancreatic, biliary and colonic disorders.

Deep Blue Medical Advances Inc.

Deep Blue Medical Advances develops a surgical mesh for hernia repair and other medical device technologies from Duke University.

DILIsym Services Inc., a Simulations Plus company

DILIsym Services provides consulting services and proprietary software to the pharmaceutical and biotech industries to develop safer and more effective drug therapies.

Research Triangle Park
HepatoSys Inc.

HepatoSys develops technologies for functional restoration and storage of organs, tissues and cells for use in research and therapeutic applications.

Ideal Health Biotechnology LLC

Ideal Health Biotechnology researches and develops dietary supplements made from plant-based compounds, including products derived from grape seed extract and algae for digestion, eye disease and diabetes.

Innovate Biopharmaceuticals Inc.

Innovate Biopharmaceuticals develops novel medicines for autoimmune and inflammatory diseases with unmet needs, including drug candidates for celiac disease and NASH.

Novan Inc.

Novan develops therapies for dermatological conditions and gastrointestinal disease using its nitric oxide-releasing nanoparticle technology.

Perspectum Diagnostics Inc.

Perspectum Diagnostics develops non-invasive medical imaging software tools. Perspectum's LiverMultiScan provides accurate and quantitative liver testing.

Wake Forest
Promethera Biosciences LLC

Promethera Biosciences develops, produces and markets cell therapeutic products, including human liver cells, to treat liver diseases.

QOL Medical LLC

QOL Medical commercializes existing and complementary new orphan products for metabolic disease and pediatric gastroenterology.

RedHill Biopharma Inc.

RedHill Biopharma develops and commercializes orally-administered, small-molecule drugs for the treatment of gastrointestinal and inflammatory diseases, including cancer. Its Raleigh site is the company's U.S. commercial headquarters.

SoyMeds Inc.

SoyMeds uses soybeans as a host to develop protein-based targets that can be used to diagnose and treat disease. SoyMeds' lead candidates include thyroglobulin and autoimmune (MS and MG) antigens.

StrideBio Inc.

StrideBio develops engineered viral vectors for gene therapy for the treatment of rare diseases. StrideBio's technology engine utilizes structure-inspired design to engineer AAV vectors which can escape pre-existing neutralizing antibodies (NAbs).

T3D Therapeutics Inc.

T3D Therapeutics is developing a disease-modifying drug therapy for Alzheimer’s disease that may improve multiple disease defects. T3D is also targeting treatments for other neurodegenerative diseases including Huntington's Disease.

Research Triangle Park
TransEnterix Inc.

TransEnterix develops and sells instruments and robotics for laparoscopic minimally invasive surgery.

UCB Biosciences Inc.

UCB Biosciences develops therapeutics for the treatment of severe, life-threatening neurological and inflammatory diseases, including epilepsy, Parkinson's disease, rheumatoid arthritis, Crohn's disease, psoriatic arthritis, lupus and osteoporosis.

Verge Therapeutics

Verge Therapeutics develops therapeutics focused on metabolic syndrome including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH).

Vivelix Pharmaceuticals Corp.

Vivelix Pharmaceuticals licenses, develops and commercializes gastroenterology and hepatology treatments.