Immunologic and Inflammatory Diseases

NCBiotech Company Directory is a comprehensive listing of North Carolina's life science industry New search

Company Title Company Description City
AimMax Therapeutics Inc.

AimMax Therapeutics researches and develops biopharmaceuticals for the treatment of infection, inflammation and pain through in-licensing or co-development with strategic partners.

Research Triangle Park
Alderon BioSciences Inc.

Alderon Biosciences develops point-of-care diagnostics.

Allergy Partners Extract Laboratory

Allergy Partners' Extract Laboratory produces extracts that are used to treat allergic disease, asthma and immunology.

ALP Life Sciences Inc.

ALP Life Sciences has formulated and markets a High-3 fish oil supplement to increase omega-3 absorption and bioavailability for the treatment of fatty liver disease and inflammatory diseases.

Black Mountain
Anémot Therapeutics Inc.

Anémot Therapeutics develops therapeutics for acute and chronic inflammation. Its lead product is being developed for severe RSV infections, cystic fibrosis and other diseases of lung injury.

Chapel Hill
Array BioPharma Inc.

Array BioPharma discovers, develops and commercializes targeted, small-molecule drugs to treat cancer.

Attagene Inc.

Attagene has developed a pathway profiling technology to evaluate the impact of pharmaceuticals and environmental chemicals on over 100 transcription factors and 48 nuclear receptors.

Bio Products Laboratory USA Inc.

Bio Products Laboratory (BPL) manufactures and distributes plasma-derived products, including intravenous immunoglobulin preparations, coagulation factors and albumin solution. U.S. Commercial Operations for BPL is based in Durham.

BioCryst Pharmaceuticals Inc.

BioCryst Pharmaceuticals designs and develops novel, small-molecule oral drugs that block key enzymes to treat rare diseases. The Durham location houses BioCryst's clinical, regulatory and executive teams.

Bryn Pharma LLC

Bryn Pharma is developing nasal solution for the administration of emergency epinephrine for the treatment of anaphylaxis.

Cellective BioTherapy Inc.

Cellective BioTherapy is developing cellular and monoclonal antibody-based platforms for treating cancers, autoimmunity and immunodeficiency.

Research Triangle Park
Clinical Sensors Inc.

Clinical Sensors (CSI) develops a near-patient test for early detection of sepsis based on nitric oxide measurements from unprocessed blood.

Research Triangle Park
Clinipace Worldwide Inc.

Clinipace provides clinical research services to pharmaceutical, biotechnology, and medical device companies globally, working across all major therapeutic areas including oncology, gastroenterology, and nephrology and urology.

Cloud Pharmaceuticals Inc.

Cloud Pharmaceuticals designs and develops novel drug molecules using computational design for a wide range of therapeutic areas including cancer, inflammation, CNS disorders and rare diseases.

Research Triangle Park
Cognosci Inc.

Cognosci develops neurorestorative therapies for Alzheimer's disease, multiple sclerosis, traumatic brain injury, nerve crush and other disease and trauma indications.

Cytex Therapeutics Inc.

Cytex Therapeutics develops bio-artificial devices to treat osteoarthritis and other musculoskeletal diseases.

Emergo Therapeutics Inc.

Emergo Therapeutics develops drugs to reduce the production of inflammatory cytokines from mast cells and improve the functioning of the immune system in various potential indications, starting with infectious diseases.

Endacea Inc.

Endacea develops A1 adenosine receptor antagonists as drug candidates for renal impairment and inflammation, including sepsis and asthma.

Research Triangle Park
Enzyvant Inc.

Enzyvant develops therapeutics for treatment of rare diseases. Their focuses are RVT-802, an investigational tissue-based therapy for immune deficiency resulting from DiGeorge Anomaly, and RVT-801, an enzyme replacement therapy to treat Farber disease.

Exodos Life Science Partners

Exodos Life Sciences advances product concepts through the 505(b)(2) process to early clinical proof-of-principle and sale. Exodus specializes in topical formulations for the treatment of pain and inflammation, cold sores and nail fungis.

Chapel Hill
FusionBio Inc.

FusionBio develops novel treatments for immune-mediated diseases, including cancer and autoimmunity.

Chapel Hill
Genencine Therapeutics LLC

Genencine Therapeutics develops mRNA vaccines for the prevention and treatment of cancer, viral diseases and autoimmune diseases, as well as mRNA therapeutic drugs for genetic diseases.

Global Vaccines Inc.

Global Vaccines is a not-for-profit company that develops vaccines against developing-country diseases such as HIV/AIDS, polio, dengue fever, malaria and viral diarrhea (rotavirus).

Chapel Hill

Grifols develops and produces plasma-derived medicines to treat chronic and acute conditions in the therapeutic areas of immunology, pulmonology, hematology, thrombolytics and neurology.

Research Triangle Park
Grifols (Clayton)

Grifols' Clayton plant is the company's primary manufacturing facility, producing proteins to treat rare diseases including immune deficiencies and genetic emphysema.


GSK develops and manufactures vaccines, medicines and consumer healthcare products, with a focus on science related to the immune system, use of genetics and advanced technologies.

Research Triangle Park
Gusto Global LLC

Gusto Global develops and provides a discovery platform that integrates advanced computational and microbiological tools to discover and develop Live Biotherapeutic Products (LBPs), and designs and develops next-generation microbiome therapeutics.

Research Triangle Park
IMMvention Therapeutix Inc.

IMMvention Therapeutix develops a platform technology that modulates innate immunity to treat unmet medical needs in cancer, autoimmune/inflammatory and infectious diseases.

Indexus Biomedical LLC

Indexus Biomedical designs, develops and manufactures instrument systems, reagents and assays for in vitro diagnostics, initially focusing on the hematology and immunology markets.

Innovate Biopharmaceuticals Inc.

Innovate Biopharmaceuticals develops novel medicines for autoimmune and inflammatory diseases with unmet needs, including drug candidates for celiac disease and NASH.

Kaio Therapy LLC

KAIO Therapy develops an immunotherapy technology to treat solid tumors.

Lundbeck NA Ltd.

Lundbeck is a pharmaceutical development company that acquires and develops products for the treatment of various human diseases, including central nervous system disorders.

Mastezellen Bio Inc.

Mastezellen Bio is developing therapeutics for the treatment of diseases and disorders with mast cell involvement.

Research Triangle Park
Mucommune LLC

Mucommune researches improved protection against infectious diseases transmitted at mucosal surfaces. Mucommune's current focus is a method to prevent sexually transmitted infections using monoclonal antibodies encapsulated in a polymeric capsule.

North Carolina Clinical Research

North Carolina Clinical Research conducts phase one through four trials at its outpatient clinical research facility. Study indications include allergy (seasonal and perennial), asthma, COPD, vaccine, migraine and bioequivalent studies.

Novan Inc.

Novan develops therapies for dermatological conditions and gastrointestinal disease using its nitric oxide-releasing nanoparticle technology.

NuBioPharma LLC

NuBioPharma develops and formulates novel liquid medications with child-friendly flavors for debilitating orphan diseases. Therapeutic areas include gout, pulmonary arterial hypertension and thrombocythemia.

OliVentures Inc.

OliVentures is developing olive oil polyphenol and omega-3 fatty acid supplements and products to support cardiovascular, breast and joint health.

Pfizer Inc. (Sanford)

Pfizer's Sanford facility manufactures clinical trial and commercial drug substance materials for conjugate vaccines.

PhotonMD Inc.

PhotonMD is developing photomedicine devices for aesthetic applications, treatment of chronic autoimmune and inflammatory diseases and eradication of MDR bacteria and HPV.

Pique Therapeutics Inc.

Pique Therapeutics develops therapeutic vaccines for the treatment of cancer.

Qura Therapeutics LLC

Qura Therapeutics is discovering therapeutics for curing HIV/AIDS. Qura is a joint venture between GSK and UNC Chapel Hill, and provides financial, material and development support for the therapies that emerge from research at the UNC HIV Cure Center.

Chapel Hill
RedHill Biopharma Inc.

RedHill Biopharma develops and commercializes orally-administered, small-molecule drugs for the treatment of gastrointestinal and inflammatory diseases, including cancer. Its Raleigh site is the company's U.S. commercial headquarters.

Renovion Inc.

Renovion is developing therapies for chronic inflammatory airways diseases including lung transplant, cystic fibrosis and bronchiectasis.

Chapel Hill
Stallergenes Greer

Stallergenes Greer develops and distributes animal and human allergy immunotherapy products and services.


TheraDiag develops and manufactures diagnostics that measure the efficiency of biotherapies in the treatment of autoimmune diseases and cancer.

Research Triangle Park
TregTherapeutics Inc.

TregTherapeutics develops tolerogenic therapies to treat autoimmune disesase. The company is currently developing a tolerogenic vaccine to eradicate multiple sclerosis.

Chapel Hill
UCB Biosciences Inc.

UCB Biosciences develops therapeutics for the treatment of severe, life-threatening neurological and inflammatory diseases, including epilepsy, Parkinson's disease, rheumatoid arthritis, Crohn's disease, psoriatic arthritis, lupus and osteoporosis.

Villaris Therapeutics Inc.

Villaris Therapeutics develops a medicine for the treatment of vitiligo.

vTv Therapeutics LLC

vTv Therapeutics is developing drug candidates to fill significant unmet medical needs such as Alzheimer’s disease, Type 2 diabetes and inflammatory disorders.

High Point
Worldwide Clinical Trials Inc.

Worldwide Clinical Trials provides phase one through phase four drug development services to the pharmaceutical and biotechnology industries.