Production and Manufacturing

908 Devices develops and makes chemical analysis products such as handheld chemical detection tools, compact analyzers and separation devices.

AccuGenomics manufactures custom gene expression tests to diagnose and monitor cancer treatment. Its technologies include Standard Nucleic Acid Quantification for RNA and DNA Sequencing for any NGS platform analysis.

Aerie Pharmaceuticals discovers, develops and commercializes first-in-class therapies for the treatment of patients with glaucoma.

Alcami provides contract drug and biologics development and manufacturing services, including formulation development, analytical chemistry, API, solid dose and parenteral drug manufacturing for both clinical and commercial markets.

Almac Clinical Services provides clinical trial material manufacturing, packaging and distribution services.

Amyris converts plant sugars into hydrocarbon molecules and produces specialty ingredients and consumer products. This site uses renewable biofarnesene to manufacture products such as biofuels, lubricants, cosmetics and other specialty chemicals.

Archer Daniels Midland's manufacturing plant in Southport makes citric acid and salts of citric acid used in soft drinks, food products and detergents. They also make yeast mannan as an animal feed ingredient.

Arspichem offers chemical product services to pharma, biotech industries, universities and research organizations to support drug discovery. Products and services include organic molecules, custom synthesis and pharmaceutical screening libraries.

Astral genetics offers a range of fee-for-service products relating to the generation and characterization of mouse and human induced pluripotent Stem Cells (iPS).

ATEX manufactures custom engineered implantable textile components for medical devices. Components are manufactured using weaving, knitting, braiding and non-woven technologies. Raw materials include polyester, bio-absorbable polymers and metals.

AveXis develops and commercializes gene therapy products for neurological genetic diseases. The Durham site is AveXis' manufacturing operations.

Avioq is an in vitro diagnostic medical device manufacturer, contract development and contract manufacturing organization operating an FDA licensed manufacturing facility and research and development laboratories.

Aweve designs and manufactures cosmeceuticals that utilize nanoparticles for the delivery of retinol, ascorbic acid and kojic acid to address wrinkles, lines, age spots and elasticity in skin.

Baxter's facility in Marion produces intravenous and peritoneal dialysis solutions, as well as empty containers and component parts for other Baxter facilities.

BD Diagnostics develops and commercializes molecular diagnostic products for women's health and various cancers.

BindusChem offers contract drug discovery and process chemistry projects for clients, synthesis of small molecules for SAR study, focused arrays and scaffolds, as well as chemical development, route scouting, process optimization and validation.

BIoCI Systems provides sterilization validation services, stability and shelf life tests and other contract laboratory testing services. BIoCI also has manufacturing capacity for custom biological indicators for sterilization efficacy monitoring.

Biogen discovers, develops and manufactures therapies for serious neurological diseases. This site houses oral solid dose and anti-sense oligonucleotide production, packaging and fill/finish operations, as well as a Global Business Services center.

BioIVT provides biological specimens, specializing in control and disease state human and animal tissues. This site develops and commercializes cell-based drug toxicity-testing products for pharmaceutical development, based on hepatocyte technologies.

BioResource International (BRI) designs, develops and manufactures unique enzymes that help poultry and swine producers optimize animal nutrition and gut health.

BioTek Ag produces plant growth regulators, nutritional products, surfactants and other specialty products to enhance soil biology and crop input effectiveness.

bluebird bio develops gene therapies and cancer immunotherapies for the treatment of genetic diseases and cancer. At its Durham site, bluebird produces lentiviral vectors for the company's gene and cell therapies.

Cambrex offers development, analytical services and manufacturing of APIs and small molecule drugs. Its Durham site provides drug substance development and manufacturing, as well as analytical services and microbiology testing services.

CasTag Biosciences provides custom AAV kits using CRISPR-based technology to label or functionally manipulate proteins of interest in cells or tissue.

Cathtek develops and manufactures catheters and related accessories.

Cellectis develops blood and bone marrow cancer cell therapies. The Raleigh location is its North American manufacturing plant.

CEM designs and develops microwave and non-microwave laboratory instrumentation and scientific methods for life sciences, analytical laboratories and processing plants.

CharGrow has developed and manufactures and distributes organic biochar-based probiotics for agriculture and horticulture.

Charter Medical designs and supplies single-use solutions for cell growth, frozen storage and biological fluid handling for the bioprocessing, cell therapy and medical device industries. CML is FDA-registered and ISO 13485-certified.

Chemring Sensors and Electronic Systems develops and manufactures chemical and biological agent detection systems, as well as explosive detection systems.

CivaTech Oncology has developed targeted implantable radiation devices to treat many cancer types. Products provide a targeted, customized radiation dose during a surgical resection procedure or in outpatient therapies to treat cancers.

CoImmune develops and manufactures cell-based therapeutics to treat unmet medical needs including cancer, autoimmune and inflammatory diseases. CoImmune also provides cGMP consulting and manufacturing of third-party clinical stage cell-based products.

Cook Medical develops and manufactures devices used in gastrointestinal endoscopy to diagnose and treat esophageal, gastric, pancreatic, biliary and colonic disorders.

Creative PEGWorks manufactures and supplies advanced functional polymer products for research. Main product lines include PEG, polysaccharides, biodegradable polyester, copolymers and PEGylation service.

Cygnus Technologies develops products and services for the biopharma industry, including host cell protein ELISA kits, immunoassay reagents and custom development of antibodies and assays.

DaVINCI Biomedical Research is an AAALAC-accredited contract lab that performs GLP and non-GLP preclinical animal studies. DaVINCI specializes in regenerative medicine, cardiovascular, orthopedic and medical device applications.

Ecoblend develops and manufactures organic weed and pest control products.

Exela Pharma Sciences develops, manufactures and markets sterile injectable pharmaceuticals and provides contract manufacturing services. The Lenoir site is a cGMP-compliant sterile manufacturing facility.

Fleming Laboratories manufactures animal pharmaceuticals.

North American Bio-Energies (NABE), doing business as Foothills Bio-Energies LLC, produces biodiesel from virgin agri-based feedstock.

Fujifilm Diosynth Biotechnologies provides biologics contract development and manufacturing. Services include cell line development, process and analytical development, clinical and commercial manufacturing and bioprocess research and development.

Gaia Herbs grows and produces certified organic herbal products, including liquid extracts, functional powders and herbal teas. All growing, manufacturing, processing, researching, packaging and distribution takes place in its North Carolina facilities.

Glenmark Pharmaceuticals discovers small-molecule drugs and biologics in the areas of oncology, respiratory disease and dermatology, and manufactures and distributes APIs and generics. The Monroe site manufactures oral solids, injectables and topicals.

Goldsboro Laboratories develops and manufactures vaccines for the swine, poultry and cattle divisions of Goldsboro Milling Company.

Grifols' manufacturing campus in Clayton produces plasma-derived medicines for the treatment of a number of rare, genetic, chronic and potentially life-threatening conditions.

Guerbet manufactures contrast media used in diagnostic imaging tests.

HeiQ ChemTex develops and manufactures specialty chemicals for the carpet, textiles, paper, coated fabrics, oil field recovery and specialty surfactants industries. Its product Bac-Shield contains a natural microbial extracted from snow crab shells.

HemoSonics is developing an in vitro diagnostic platform that measures the evolving stiffness of forming blood clots within a consumable test cartridge. Its technology assists with the management of coagulation dysfunctions at the point of care.

HOMS develops, manufactures and markets natural products for pest management.