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Showing 1 - 50 of 55 results found.
Company | Activity | Company Description | Location | |
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Company AskBio | Activity: Research and Development | Company Description Asklepios BioPharmaceutical (AskBio) uses adeno-associated virus (AAV) technology to develop and manufacture gene therapies for rare diseases and other genetic disorders. | Location Research Triangle Park | |
Company Astellas Gene Therapies | Activity: Production and Manufacturing | Company Description Astellas Gene Therapies manufactures AAV gene therapy products for rare diseases. | Location Sanford | |
Company Atsena Therapeutics Inc. | Activity: Research and Development | Company Description Atsena Therapeutics is developing ocular gene therapies to reverse or prevent blindness. | Location Durham | |
Company Azenta Life Sciences RTP | Activity: Contract Research and Testing | Company Description Azenta Life Sciences, formerly Genewiz, provides custom DNA sequencing, gene synthesis, genomics, next-generation sequencing and molecular biology in a GLP/cGMP regulatory environment. | Location Research Triangle Park | |
Company Beam Therapeutics | Activity: Production and Manufacturing | Company Description Beam Therapeutics will manufacture precision genetic medicines through the use of base editing technology at its RTP site. | Location Durham | |
Company Bedrock Therapeutics Inc. | Activity: Research and Development | Company Description Bedrock Therapeutics is an AAV research and development company developing platform technologies and therapeutics. | Location Raleigh | |
Company BioCytics Inc. | Activity: Research and Development | Company Description BioCytics researches and develops personalized cellular immunotherapy cancer therapies with the latest technology and equipment. BioCytics also offers contract R&D and is co-located with its sister company, the Carolina BioOncology Institute. | Location Huntersville | |
Company Black Swan Pharmaceuticals Inc. | Activity: Research and Development | Company Description Black Swan Pharmaceuticals is developing preclinical gene targeting therapeutics for motor neurone disease (MND) / Amyotrophic Lateral Sclerosis (ALS) and other neurological disorders. | Location Wake Forest | |
Company BridgeBio Gene Therapy | Activity: Research and Development | Company Description BridgeBio Gene Therapy is developing a gene therapy for the treatment of a monogenic disease that presents in childhood. | Location Raleigh | |
Company CARsgen Therapeutics | Activity: Production and Manufacturing | Company Description CARsgen Therapeutics develops innovative CAR-T cell therapies for the treatment of hematological malignancies and solid tumors. | Location Durham | |
Company CasTag Biosciences Inc. | Activity: Production and Manufacturing | Company Description CasTag Biosciences provides custom AAV kits. It uses CRISPR knock-in technology to produce genome-wide arrayed libraries with a variety of donors for endogenous protein analysis in cells and tissue. | Location Durham | |
Company Cellectis | Activity: Production and Manufacturing | Company Description Cellectis develops gene-editing technologies and cell therapies to treat cancers of the blood, myeloid, and lymphatic systems. The Raleigh location is the company's GMP manufacturing plant for Cellectis' portfolio of UCART drug products. | Location Raleigh | |
Company Cellective BioTherapy Inc. | Activity: Research and Development | Company Description Cellective BioTherapy is developing cellular and monoclonal antibody-based platforms for treating cancers, autoimmunity and immunodeficiency through the manipulation of B cells and their functional subsets. | Location Chapel Hill | |
Company CLAIRIgene LLC | Activity: Research and Development | Company Description CLAIRIgene develops viral vector platforms for gene therapy products to treat central nervous system diseases and conditions. | Location Durham | |
Company Couragen Biopharmaceutics LLC | Activity: Research and Development | Company Description Couragen Biopharmaceutics develops gene and protein therapy products for preclinical and clinical use for the treatment of genetic and chronic diseases. Couragen also provides custom adeno-associated virus vectors as a tool for laboratory research. | Location Chapel Hill | |
Company Creyon Bio | Activity: Research and Development | Company Description Creyon Bio is a drug development company engineering RNA-based medicines and their components. | Location Research Triangle Park | |
Company Denizen Biologics LLC | Activity: Research and Development | Company Description Denizen Biologics develops gene therapy vectors to enhance the capability of genetic medicine and improve the outcomes for patients. | Location Cary | |
Company Encoded Therapeutics Inc. | Activity: Production and Manufacturing | Company Description Encoded is developing and commercializing gene therapies for pediatric central nervous system (CNS) disorders with its cell-selective targeting and regulation platform. | Location Morrisville | |
Company Enzerna Biosciences Inc. | Activity: Research and Development | Company Description Enzerna Biosciences is a pre-clinical stage company that is leveraging its proprietary RNA editing technology to develop long-term curative gene therapies for rare genetic disorders such as Huntington's Disease and Myotonic Dystrophy. | Location Morrisville | |
Company Epigenos Biosciences Inc. | Activity: Research and Development | Company Description Epigenos Biosciences develops personalized epigenome-based therapeutics that leverage site-specific DNA binding technologies to treat disease at the root of gene mis-regulation. | Location Morrisville | |
Company FastBack Bio LLC | Activity: Research and Development | Company Description FastBack Bio is developing CAR-T therapy for treatment of solid tumors. | Location Raleigh | |
Company FUJIFILM Diosynth Biotechnologies USA Inc. (Morrisville) | Activity: Production and Manufacturing | Company Description FUJIFILM Diosynth Biotechnologies is a contract development and manufacturing organization for biologics, vaccines, cell and gene therapies, and oncolytic viruses. Services include cell line development, process and analytical development, clinical and commercial manufacturing and bioprocess research and development. | Location Morrisville | |
Company General Biosystems Inc. | Activity: Contract Research and Testing | Company Description General Biosystems provides gene synthesis, molecular biology, and protein expression and purification services. | Location Durham | |
Company GeneVentiv Therapeutics Inc. | Activity: Research and Development | Company Description GeneVentiv Therapeutics is a gene therapy company developing treatments for blood diseases and disorders, including treatments for Hemophilia A and B with or without inhibitors and for Hemophilia Arthropathy, a degenerative joint disease. | Location Raleigh | |
Company GENIE Therapeutics | Activity: Research and Development | Company Description Genie Therapeutics develops a cosmetic gene therapy in a topical cream formulation to reduce wrinkles, regenerate collagen and restore aging skin. The delivery platform will be used to develop wound healing drugs. | Location Winston-Salem | |
Company Immorna Biotherapeutics Inc. | Activity: Research and Development | Company Description Immorna Biotherapeutics develops self-replicating and conventional mRNA-based therapeutics and vaccines. | Location Raleigh | |
Company Inceptor Bio LLC | Activity: Research and Development | Company Description Inceptor Bio develops next-generation cell therapy platforms, across multiple cell types, to cure cancers. Its site includes a manufacturing facility for production of its therapies. | Location Raleigh | |
Company Isolere Bio Inc. | Activity: Research and Development | Company Description Isolere Bio is developing novel, non-chromatographic technologies for the purification of biologics such as antibodies, gene delivery vectors and personalized cell therapies. | Location Durham | |
Company Jaguar Gene Therapy LLC (Analytical Development) | Activity: Research and Development | Company Description Jaguar Gene Therapy develops gene therapies for patients suffering from severe genetic diseases. The company's analytical development lab is located in Durham. | Location Durham | |
Company Jaguar Gene Therapy LLC (Process Sciences Lab) | Activity: Research and Development | Company Description Jaguar Gene Therapy develops gene therapies for patients suffering from severe genetic diseases. The company's process sciences lab is located in Cary. | Location Cary | |
Company Kriya Therapeutics Inc. | Activity: Production and Manufacturing | Company Description Kriya Therapeutics develops AAV-based gene therapies for the treatment of type 1 and type 2 diabetes, severe obesity, and other indications. This location is the company's internal manufacturing facility. | Location Morrisville | |
Company Life Edit Therapeutics | Activity: Research and Development | Company Description Life Edit Therapeutics, an ElevateBio company, identifies novel genome editing systems from a database of microbial genomes. These systems are then developed for use as human therapeutics, both in-house and through external partnerships. | Location Durham | |
Company Locus Biosciences Inc. | Activity: Research and Development | Company Description Locus Biosciences is developing CRISPR-engineered bacteriophage (“crPhage”) products that kill target bacteria by irreversibly destroying their DNA while leaving the many species of beneficial bacteria in the body unharmed. | Location Morrisville | |
Company NabGen Inc. | Activity: Research and Development | Company Description NabGen has developed a universal antibody suppressant technology to inhibit anti-drug and autoimmune antibodies, including suppression of pre-existing immunity and re-administration barriers to gene therapies based on adeno-associated virus (AAV) vectors. | Location Durham | |
Company NeuroGT Inc. | Activity: Research and Development | Company Description NeuroGT is developing gene therapy products to treat rare neurogenetic diseases. | Location Chapel Hill | |
Company Novartis Gene Therapies | Activity: Production and Manufacturing | Company Description Novartis Gene Therapies develops and commercializes gene therapies for patients and families devastated by rare and life-threatening neurological genetic diseases. The Durham site is Novartis Gene Therapies' manufacturing operations. | Location Durham | |
Company OncoTrap Inc. | Activity: Research and Development | Company Description OncoTrap is developing a nucleic acid delivery platform for accommodating nucleic acid-based therapeutics, designed to deliver therapeutic genes to tumor sites. | Location Research Triangle Park | |
Company Opus Genetics Inc. | Activity: Research and Development | Company Description Opus Genetics is a clinical-stage gene therapy company developing treatments for inherited retinal diseases. | Location Research Triangle Park | |
Company Pfizer Inc. (Durham) | Activity: Research and Development | Company Description Pfizer develops gene therapies to treat rare genetic central nervous system (CNS) and neuromuscular diseases. Pfizer's BioTherapeutics Pharmaceutical Sciences site in Durham houses clinical manufacturing space and analytical research development laboratories. | Location Durham | |
Company Pfizer Inc. (Sanford) | Activity: Production and Manufacturing | Company Description Pfizer's Sanford facility manufactures clinical trial and commercial materials for conjugate vaccines and gene therapies. | Location Sanford | |
Company PhosphoGam Inc. | Activity: Research and Development | Company Description PhosphoGam is developing allogeneic cell immunotherapies using gamma/delta T-cells to treat a variety of cancers. | Location Durham | |
Company Precision BioSciences Inc. (Durham) | Activity: Research and Development | Company Description Precision BioSciences is a clinical stage in vivo gene editing company using its novel ARCUS genome editing platform to develop new treatment options for genetic and infectious diseases. | Location Durham | |
Company Precision Biosciences Manufacturing Center for Advanced Therapeutics (RTP) | Activity: Production and Manufacturing | Company Description Precision BioSciences is a clinical stage in vivo gene editing company using its novel ARCUS genome editing platform to develop new treatment options for genetic and infectious diseases. | Location Research Triangle Park | |
Company ProKidney (Winston-Salem) | Activity: Production and Manufacturing | Company Description ProKidney manufactures cell therapy products that use a patient's own cells to restore damaged kidney tissues by engrafting into, repairing or replacing damaged tissues or organs. | Location Winston-Salem | |
Company RainBio Inc. | Activity: Research and Development | Company Description RainBio is developing AAV (adeno-associated virus) gene therapy corneal treatments to address the unmet need of treatment of rare corneal blinding diseases. | Location Raleigh | |
Company Resilience (Durham) | Activity: Production and Manufacturing | Company Description National Resilience manufactures viral vectors, a component of cell and gene therapies. | Location Durham | |
Company Sarepta Therapeutics Inc. (Durham) | Activity: Research and Development | Company Description Sarepta Therapeutics develops precision genetic medicine treatments for Duchenne muscular dystrophy (DMD), Limb-girdle muscular dystrophy (LGMD) and other central nervous system (CNS) disorders. Sarepta's Gene Editing Innovation Center is in Durham. | Location Durham | |
Company SNP Therapeutics LLC | Activity: Research and Development | Company Description SNP Therapeutics develops genetic tests to identify genetic variant patterns that contribute to disease. SNPT also designs nutritional therapeutics to treat metabolic disorders. | Location Kannapolis | |
Company Sumitomo Pharma America Inc. (Cary) | Activity: Research and Development | Company Description Sumitomo Pharma America develops regenerative therapeutics for rare diseases such as congenital athymia. | Location Cary | |
Company Taysha Gene Therapies Inc. | Activity: Production and Manufacturing | Company Description Taysha Gene Therapies develops and manufactures gene therapies for the treatment of monogenic diseases of the central nervous system (CNS), both in rare and large patient populations. | Location Research Triangle Park |