NCBiotech Company Directory

A comprehensive listing of North Carolina's life science industry

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Showing 1 - 50 of 54 results found.

Activity Company Description Location
Company Sio Gene Therapies Activity: Research and Development Research and Development Company Description Sio Gene Therapies develops gene therapies to treat neurologic conditions. Location Durham
Company StrideBio Inc. Activity: Research and Development Research and Development Company Description StrideBio develops engineered viral vectors for gene therapy for the treatment of rare diseases. StrideBio's technology engine utilizes structure-inspired design to engineer AAV vectors which can escape pre-existing neutralizing antibodies (NAbs). Location Research Triangle Park
Company AavantiBio (RTP) Activity: Research and Development Research and Development Company Description AavantiBio is developing novel gene transfer and gene editing therapies for the treatment of rare and ultra-rare genetic diseases. Location Research Triangle Park
Company ArunA Bio Activity: Research and Development Research and Development Company Description Aruna Bio develops neural exosomes for the treatment of neurodegenerative diseases. The company is utilizing its proprietary neural exosome platform and manufacturing capability to develop a pipeline of therapeutics. Location Raleigh
Company AskBio Activity: Research and Development Research and Development Company Description Asklepios BioPharmaceutical (AskBio) uses adeno-associated virus (AAV) technology to develop and manufacture gene therapies for rare diseases and other genetic disorders. Location Research Triangle Park
Company Astellas Gene Therapies Activity: Production and Manufacturing Production and Manufacturing Company Description Astellas Gene Therapies manufactures AAV gene therapy products for rare diseases. Location Sanford
Company Atsena Therapeutics Inc. Activity: Research and Development Research and Development Company Description Atsena Therapeutics is developing ocular gene therapies to reverse or prevent blindness. Location Durham
Company Azenta Life Sciences RTP Activity: Contract Research and Testing Contract Research and Testing Company Description Azenta Life Sciences, formerly Genewiz, provides custom DNA sequencing, gene synthesis, genomics, next-generation sequencing and molecular biology in a GLP/cGMP regulatory environment. Location Research Triangle Park
Company Beam Therapeutics Activity: Production and Manufacturing Production and Manufacturing Company Description Beam Therapeutics will manufacture precision genetic medicines through the use of base editing technology at its RTP site. Location Durham
Company Bedrock Therapeutics Inc. Activity: Research and Development Research and Development Company Description Bedrock Therapeutics is an AAV research and development company developing platform technologies and therapeutics. Location Raleigh
Company BioCytics Inc. Activity: Research and Development Research and Development Company Description BioCytics researches and develops personalized cellular immunotherapy cancer therapies with the latest technology and equipment. BioCytics also offers contract R&D and is incubated within the Carolina BioOncology Institute. Location Huntersville
Company Black Swan Pharmaceuticals Inc. Activity: Research and Development Research and Development Company Description Black Swan Pharmaceuticals is developing preclinical gene targeting therapeutics for motor neurone disease (MND) / Amyotrophic Lateral Sclerosis (ALS) and other neurological disorders. Location Wake Forest
Company BridgeBio Gene Therapy Activity: Research and Development Research and Development Company Description BridgeBio Gene Therapy is developing a gene therapy for the treatment of a monogenic disease that presents in childhood. Location Raleigh
Company CARsgen Therapeutics Activity: Production and Manufacturing Production and Manufacturing Company Description CARsgen Therapeutics develops innovative CAR-T cell therapies for the treatment of hematological malignancies and solid tumors. Location Durham
Company CasTag Biosciences Inc. Activity: Production and Manufacturing Production and Manufacturing Company Description CasTag Biosciences provides custom AAV kits. It uses CRISPR knock-in technology to produce genome-wide arrayed libraries with a variety of donors for endogenous protein analysis in cells and tissue. Location Durham
Company Cellectis Activity: Production and Manufacturing Production and Manufacturing Company Description Cellectis develops gene-editing technologies and cell therapies to treat cancers of the blood, myeloid, and lymphatic systems. The Raleigh location is the company's GMP manufacturing plant for Cellectis' portfolio of UCART drug products. Location Raleigh
Company Cellective BioTherapy Inc. Activity: Research and Development Research and Development Company Description Cellective BioTherapy is developing cellular and monoclonal antibody-based platforms for treating cancers, autoimmunity and immunodeficiency through the manipulation of B cells and their functional subsets. Location Research Triangle Park
Company CLAIRIgene LLC Activity: Research and Development Research and Development Company Description CLAIRIgene develops viral vector platforms for gene therapy products to treat central nervous system diseases and conditions. Location Durham
Company Couragen Biopharmaceutics LLC Activity: Research and Development Research and Development Company Description Couragen Biopharmaceutics develops gene and protein therapy products for preclinical and clinical use for the treatment of genetic and chronic diseases. Couragen also provides custom adeno-associated virus vectors as a tool for laboratory research. Location Chapel Hill
Company Denizen Biologics LLC Activity: Research and Development Research and Development Company Description Denizen Biologics develops gene therapy vectors to enhance the capability of genetic medicine and improve the outcomes for patients. Location Cary
Company Encoded Therapeutics Inc. Activity: Production and Manufacturing Production and Manufacturing Company Description Encoded is developing and commercializing gene therapies for pediatric central nervous system (CNS) disorders with its cell-selective targeting and regulation platform. Location Raleigh
Company Enzerna Biosciences Inc. Activity: Research and Development Research and Development Company Description Enzerna Biosciences is a pre-clinical stage company that is leveraging its proprietary RNA editing technology to develop long-term curative gene therapies for rare genetic disorders such as Huntington's Disease and Myotonic Dystrophy. Location Morrisville
Company Enzyvant Inc. Activity: Research and Development Research and Development Company Description Enzyvant, a subsidiary of Sumitovant Biopharma, develops regenerative therapeutics for rare diseases such as congenital athymia. Location Durham
Company Epigenos Biosciences Inc. Activity: Research and Development Research and Development Company Description Epigenos Biosciences develops personalized epigenome-based therapeutics that leverage Cas9 technology to treat disease at the root of gene mis-regulation. Location Morrisville
Company FastBack Bio LLC Activity: Research and Development Research and Development Company Description FastBack Bio is developing CAR-T therapy for treatment of solid tumors. Location Raleigh
Company General Biosystems Inc. Activity: Contract Research and Testing Contract Research and Testing Company Description General Biosystems provides gene synthesis, molecular biology, and protein expression and purification services. Location Durham
Company GeneVentiv Therapeutics Inc. Activity: Research and Development Research and Development Company Description GeneVentiv Therapeutics is a gene therapy company developing treatments for blood diseases and disorders, including treatments for Hemophilia A and B with or without inhibitors and for Hemophilia Arthropathy, a degenerative joint disease. Location Raleigh
Company GENIE Therapeutics Activity: Research and Development Research and Development Company Description Genie Therapeutics develops a cosmetic gene therapy in a topical cream formulation to reduce wrinkles, regenerate collagen and restore aging skin. The delivery platform will be used to develop wound healing drugs. Location Winston-Salem
Company Inceptor Bio LLC Activity: Research and Development Research and Development Company Description Inceptor Bio develops next-generation cell therapy platforms, across multiple cell types, to cure cancers. Its site includes a manufacturing facility for production of its therapies. Location Raleigh
Company Isolere Bio Inc. Activity: Research and Development Research and Development Company Description Isolere Bio is developing novel, non-chromatographic technologies for the purification of biologics such as antibodies, gene delivery vectors and personalized cell therapies. Location Durham
Company Jaguar Gene Therapy LLC Activity: Research and Development Research and Development Company Description Jaguar Gene Therapy develops gene therapies for patients suffering from severe genetic diseases. Location Cary
Company Kriya Therapeutics Inc. Activity: Production and Manufacturing Production and Manufacturing Company Description Kriya Therapeutics develops AAV-based gene therapies for the treatment of type 1 and type 2 diabetes, severe obesity, and other indications. This location is the company's internal manufacturing facility. Location Morrisville
Company Life Edit Therapeutics Activity: Research and Development Research and Development Company Description Life Edit Therapeutics, an ElevateBio company, identifies novel genome editing systems from a database of microbial genomes. These systems are then developed for use as human therapeutics, both in-house and through external partnerships. Location Morrisville
Company Locus Biosciences Inc. Activity: Research and Development Research and Development Company Description Locus Biosciences is developing CRISPR-engineered bacteriophage (“crPhage”) products that kill target bacteria by irreversibly destroying their DNA while leaving the many species of beneficial bacteria in the body unharmed. Location Morrisville
Company NabGen Inc. Activity: Research and Development Research and Development Company Description NabGen has developed a co-therapy designed to overcome pre-existing immunity and re-administration barriers of gene therapies based on adeno-associated virus (AAV) vectors. Location Durham
Company NeuroGT Inc. Activity: Research and Development Research and Development Company Description NeuroGT is developing gene therapy products to treat rare neurogenetic diseases. Location Chapel Hill
Company Novartis Gene Therapies Activity: Production and Manufacturing Production and Manufacturing Company Description Novartis Gene Therapies develops and commercializes gene therapies for patients and families devastated by rare and life-threatening neurological genetic diseases. The Durham site is Novartis Gene Therapies' manufacturing operations. Location Durham
Company OncoTrap Inc. Activity: Research and Development Research and Development Company Description OncoTrap is developing a nucleic acid delivery platform for accommodating nucleic acid-based therapeutics, designed to deliver therapeutic genes to tumor sites. Location Research Triangle Park
Company Opus Genetics Inc. Activity: Research and Development Research and Development Company Description Opus Genetics is developing a gene therapy to treat ultra-rare retinal degenerative diseases. Location Raleigh
Company Pfizer Inc. (Durham) Activity: Research and Development Research and Development Company Description Pfizer develops gene therapies to treat rare genetic central nervous system (CNS) and neuromuscular diseases. Pfizer's Pfizer's BioTherapeutics Pharmaceutical Sciences site in Durham houses clinical manufacturing space and analytical research development laboratories. Location Durham
Company Pfizer Inc. (Sanford) Activity: Production and Manufacturing Production and Manufacturing Company Description Pfizer's Sanford facility manufactures clinical trial and commercial materials for conjugate vaccines and gene therapies. Location Sanford
Company PhosphoGam Inc. Activity: Research and Development Research and Development Company Description PhosphoGam is developing allogeneic cell immunotherapies using gamma/delta T-cells to treat a variety of cancers. Location Durham
Company Precision BioSciences Inc. (Durham) Activity: Research and Development Research and Development Company Description Precision BioSciences utilizes a proprietary genome editing method called ARCUS to treat cancers and genetic diseases, and enable the development of safer, more productive food sources. Location Durham
Company Precision Biosciences Manufacturing Center for Advanced Therapeutics (RTP) Activity: Production and Manufacturing Production and Manufacturing Company Description Precision BioSciences utilizes a proprietary genome editing method called ARCUS to treat cancers and genetic diseases. The MCAT facility produces genome-edited, off-the-shelf CAR T-cell therapy products. Location Research Triangle Park
Company ProKidney Activity: Production and Manufacturing Production and Manufacturing Company Description ProKidney manufactures cell therapy products that use a patient's own cells to restore damaged kidney tissues by engrafting into, repairing or replacing damaged tissues or organs. Location Winston-Salem
Company RainBio Inc. Activity: Research and Development Research and Development Company Description RainBio is developing AAV (adeno-associated virus) gene therapy corneal treatments to address the unmet need of treatment of rare corneal blinding diseases. Location Raleigh
Company Resilience (Durham) Activity: Production and Manufacturing Production and Manufacturing Company Description National Resilience manufactures lentiviral vectors, a component of cell and gene therapies. Location Durham
Company Seeing Medicines Inc. Activity: Research and Development Research and Development Company Description Seeing Medicines is developing regenerative medicine treatments to restore and maintain vision in people with macular degenerative diseases such as Age-related Macular Degeneration (AMD), Best Disease and Stargardt's Disease.. Location Arden
Company SNP Therapeutics LLC Activity: Research and Development Research and Development Company Description SNP Therapeutics develops genetic tests to identify genetic variant patterns that contribute to disease. SNPT also designs nutritional therapeutics to treat metabolic disorders. Location Kannapolis
Company Taysha Gene Therapies Inc. Activity: Production and Manufacturing Production and Manufacturing Company Description Taysha Gene Therapies develops and manufactures gene therapies for the treatment of monogenic diseases of the central nervous system (CNS). Location Durham