Biomarkers

AccuBeing creates three-dimensional cancer organoids from patients' cancer cells, which are used to test novel drug therapies, transcriptomic and epigenetic analyses. Results are used to match the patient with personalized clinical trials.

Adámas Nanotechnologies develops and produces fluorescent nanodiamond particles for life science, medical and industrial applications, including life science research, drug delivery, bioimaging, anti-counterfeiting, oil additives and cosmetics.

Alderon Biosciences develops point-of-care diagnostics.

Almac offers services for biomarker discovery, assay development/validation/testing and companion diagnostic co-development. Testing platforms include NGS, Microarray, qPCR and IHC. Regulatory and bioinformatics services are also available.

The Division of Therapeutic Research and Development at Atrium Health conducts clinical studies, patient-focused translational research and outcomes research.

Avioq develops and manufactures FDA-approved and CE-marked immunodiagnostic assays. Products include HIV and HTLV assays, recombinant proteins and synthetic peptides and labware supplies. Avioq also offers contract IVD development and manufacturing.

Bent Creek Institute is a 501(c)3 non-profit botanical research and economic development organization serving primarily North Carolina-based natural products companies seeking to innovate botanical wellness solutions.

BioAgilytix is a bioanalytical lab specializing in large-molecule bioanalysis, offering PK, immunogenicity, biomarkers and cell-based assays in support of the development and release testing of biologics and small-molecule therapeutics.

Biofluidica is developing novel instrumentation for the isolation and analysis of circulating biomarkers, including circulating tumor cells, in cancer patients.

bioMérieux develops in vitro products to diagnose infectious diseases, cancer and cardiovascular disease and to detect microorganisms in agri-foods, pharmaceuticals and cosmetics.

BioRxn develops NMR-based metabolomic technology, including bioreactor and artificial liver systems, for non-invasive monitoring of metabolic biomarkers. BioRxn also provides conventional metabolomic services.

BioVendor develops, manufactures and sells biological reagents and research products, including enzyme-linked immunosorbent assay (ELISA) kits, antibodies, proteins and other molecules for life science research. This location is the U.S. headquarters.

Burleson Research Technologies provides laboratory services to the biotechnology, pharmaceutical, chemical manufacturing and health care industries with proof-of-concept, preclinical, clinical and toxicology studies.

Charles River Laboratories' Oncology Center of Excellence provides in vivo and in vitro oncology and immuno-oncology research services.

Covance, the drug development business of LabCorp, provides a wide range of early-stage and late-stage product development services primarily to the pharmaceutical and biotechnology industries.

Curl Bio develops drugs for the interrelated set of disorders involving Type 2 diabetes, obesity, fatty liver disease, metabolic syndrome and associated complications.

DILIsym Services provides consulting services and proprietary software to the pharmaceutical and biotech industries to develop safer and more effective drug therapies.

Eurofins Craft Technologies provides analytical and method development services to measure nutritional components in blood, tissues, dietary supplements, food and animal feed.

Galaxy Diagnostics develops assays and provides molecular and serology testing for flea- and tick-borne infectious disease for physicians, veterinarians and clinical research.

GEM Tox Labs conducts research focused on cancer biotechnology, food safety and toxicology, with a special emphasis on cancer biomarker discovery and validation.

Genetron Health Technologies provides mutation detection assays using its liquid biopsy platform, as well as various genetic assays to support both clinical and basic research. Genetron also offers custom assay development.

Gusto Global develops and provides a discovery platform that integrates advanced computational and microbiological tools to discover and develop Live Biotherapeutic Products (LBPs), and designs and develops next-generation microbiome therapeutics.

Indexus Biomedical designs, develops and manufactures instrument systems, reagents and assays for in vitro diagnostics, initially focusing on the hematology and immunology markets.

Intarcia Therapeutics is developing a continuous subcutaneous delivery system for the treatment of Type 2 diabetes. The RTP location discovers and develops peptide therapeutic drugs to augment Intarcia's drug delivery platform.

Jericho Sciences is developing antiviral therapeutics and corresponding personalized diagnostics for the clinical management of HIV-1 infection.

LCMS provides LC/MS services for the identification and quantification of compounds in biological and environmental matrices. LCMS specializes in detecting cross contamination from food and drug manufacturing and also provides LC/MS training.

MDxHealth develops epigenetic technologies to personalize the diagnosis and treatment of cancer.

MoyoMedical develops home-based early detection tests for pregnancy complications like preeclampsia and eclampsia for use in low-resource settings.

The NCSU Technology Incubator at Centennial Campus offers a program and facilities specifically designed for tech start-ups with high-impact potential.

Omicsoft designs software for biomarker data management, visualization and analysis.

OpAns provides analytical services to support discovery, preclinical, toxicology and clinical studies.

Path BioAnalytics develops rheological assays for testing trans-mucosal drug delivery systems, mucolytic compounds, inhaled medications for respiratory diseases, antimicrobials and treatments for diseases that impact the body's mucosal layers.

QNS Group offers consulting in translational medicine, analytical biotechnology, biopharmaceuticals, medical devices and diagnostics. Services include virtual discovery, product design and development, including regulatory advice.

Q² Solutions offers clinical trials lab services to biopharma, device and diagnostics customers. Services include central laboratories, bioanalytical, ADME, genomics, biomarkers and companion diagnostics to support drug discovery and precision medicine.

RTI, an independent, nonprofit institute, offers scientific and technical expertise in social and laboratory sciences, engineering and international development to government and commercial clients worldwide.

Sapere Bio develops biomarkers of aging for clinical use to help physicians predict risk of chemotherapy-induced toxicities and surgery-associated adverse events in various patient groups.

ScitoVation supports and advances research on the effects of chemical compounds on human health. ScitoVation works with clients to develop safer pharmaceuticals, food ingredients, agricultural chemicals, commodity chemicals and consumer products.

Shoaf Scientific Consultants provides research and development services in plant redox bioenergetics, antimicrobial surface technologies and molecular photochemical studies in singlet oxygen and superoxide-free radical anion as applied to aging.

SoyMeds uses soybeans as a host to develop protein-based targets that can be used to diagnose and treat disease. SoyMeds' lead candidates include thyroglobulin and autoimmune (MS and MG) antigens.

Synapse Biosciences develops biomarker preparations and customized assays for the diagnostic determination of medication compliance. Synapse also provides diagnostic testing services and reporting for medication compliance in clinical trials.

Tenax Therapeutics develops and commercializes pharmaceutical products for the critical care market.

ZenBio provides contract research services and human tissues and cells for drug discovery, especially in the area of human metabolic disease and dermatology.