Biomarkers

AccuBeing creates three-dimensional cancer organoids from patients' cancer cells, which are used to test novel drug therapies, transcriptomic and epigenetic analyses. Results are used to match the patient with personalized clinical trials.

Adámas Nanotechnologies develops and produces fluorescent nanodiamond particles for life science, medical and industrial applications, including life science research, drug delivery, bioimaging, anti-counterfeiting, oil additives and cosmetics.

Alderon Biosciences develops point-of-care diagnostics.

Almac offers services for biomarker discovery, assay development/validation/testing and companion diagnostic co-development. Testing platforms include NGS, Microarray, qPCR and IHC. Regulatory and bioinformatics services are also available.

Array BioPharma discovers, develops and commercializes targeted, small-molecule drugs to treat cancer.

Avazyme provides field and GLP laboratory testing for sectors including agchem, agbiotech, food and beverage producers and retailers, and pharmaceuticals. Capabilities include mass spectrometry, immunochemistry, microbiology and molecular biology.

Baebies develops and commercializes products and services based on digital microfluidics and other technology that ensure early disease detection and comprehensive diagnosis for children.

Bio-Val provides bioassay development, method validation, reagent production and characterization, feasibility and medical writing services.

BioCytics researches and develops personalized cellular immunotherapy cancer therapies with the latest technology and equipment. BioCytics also offers contract R&D and is incubated within the Carolina BioOncology Institute.

BioMedomics develops point-of-care (POC) diagnostics in hematology oncology, virology, women’s health and dermatology.

bioMONTR provides a broad range of CLIA-certified high-complexity laboratory testing, including assay/IVD protocol development, validation design, performance evaluation testing, drug trials and collaborative studies and regulatory/quality control.

BioVendor develops, manufactures and sells biological reagents and research products, including enzyme-linked immunosorbent assay (ELISA) kits, antibodies, proteins and other molecules for life science research. This location is the U.S. headquarters.

Burleson Research Technologies provides laboratory services to the biotechnology, pharmaceutical, chemical manufacturing and health care industries with proof-of-concept, preclinical, clinical and toxicology studies.

Charles River Laboratories' Oncology Center of Excellence provides in vivo and in vitro oncology and immuno-oncology research services.

Creative Scientist offers rapid in vitro ADME-TOX testing, 96-well drug permeability, cytotoxicity, cell-signalling, and gene-expression analyses; testing of T-cell activation and cytotoxicity, FACS analysis, high-content imaging; reporter assays.

Diabetic Health develops coatings to improve the longevity and performance of continuous glucose monitoring sensors (CGM) and insulin infusion sets used in diabetes management.

Drumetix provides bioanalytical support for drug metabolism, pharamacokinetics and toxicokinetic (DMPK, ADME) studies, as well as LC-MS/MS analysis of small-molecule biomarkers, such as neurotransmitters, all-trans retinoic acid and creatinine.

Friley Consulting provides preclinical analysis and clinical sample analysis for biotech companies. It also offers research management services, such as data analysis, report writing, protocol development, consulting and clinical trial management.

Gateway Research Park is a joint venture created by NC A&T State University and the University of North Carolina Greensboro to catalyze university research, innovation and economic development.

Gemelli Biotech develops diagnostics and therapeutics for microbiome diseases.

Genewiz provides custom DNA sequencing, gene synthesis, genomics, next-generation sequencing and molecular biology in a GLP/cGMP regulatory environment.

Helix3 is a GLP contract research laboratory that designs and conducts customized in vitro and in vivo genetic toxicology studies for US and EU regulatory submissions.

Immune Diagnostics provides advanced testing services to developers of immuno-therapeutics and vaccines using its proprietary technologies. The company's pipeline includes related clinical diagnostics, point-of-care and companion assays and systems.

Indiomics uses machine learning and protein biomarker expression levels to identify connections between human cells and common chemical exposures.

ILS provides GLP toxicology, histopathology, molecular biology and research and development services to government and commercial clients in agro-chemical, biopharmaceutical and environmental industries.

Jericho Sciences is developing antiviral therapeutics and corresponding personalized diagnostic assays which specifically address the limitations of current combination antiretroviral therapy (cART) in the clinical management of HIV-1 infection.

Laudiss Labs uses advanced proprietary platform technologies for quantitative DNA and protein testing of GMOs, foodborne pathogens and mycotoxins in food and feed.

Lucerno Dynamics is commercializing a noninvasive device for quality assurance and control in nuclear medicine imaging. Future applications of the technology include rheumatoid arthritis, immunotherapy, nuclear medicine and chemotherapy assessment.

Metabolon is advancing the science of metabolomics for the clinic and life sciences research. Its technology and data are used for biomarker discovery, diagnostic test development, and genomics and population health initiatives.

ASSIST develops nano-enabled wearable sensor platforms. ASSIST’s platforms are creating innovative, battery-free, body-powered, wearable health monitoring systems for correlation of health and environment.

OncoTAb develops and commercializes diagnostic blood tests designed to detect breast cancer and develops an immunotherapy for the treatment of pancreatic cancer.

Parion Sciences develops therapies to treat defects of the innate mucosal defense system in respiratory and ophthalmology diseases.

Personalized Medicine Partners faciltates the translation of science into products and platforms for clinical development, enabling commercialization of novel treatments and laboratory tests, with a focus in the field of precision medicine.

Quanticision Diagnostics measures tissues biomarkers for solid tumor diagnosis and supplies multi-unit plates for high throughput immunoblot analysis.

Ribometrix is a platform therapeutics company discovering small-molecule drugs that target functional RNA structures to create new avenues to treat human disease.

Sanesco develops clinical tools for healthcare providers, such as neuroendocrine analytical testing, nutritional support formulas and patient-centered clinical review. The NeuroLab division conducts research and development of in vitro diagnostic tools.

ScitoVation supports and advances research on the effects of chemical compounds on human health. ScitoVation works with clients to develop safer pharmaceuticals, food ingredients, agricultural chemicals, commodity chemicals and consumer products.

Shoaf Scientific Consultants provides research and development services in plant redox bioenergetics, antimicrobial surface technologies and molecular photochemical studies in singlet oxygen and superoxide-free radical anion as applied to aging.

SoyMeds uses soybeans as a host to develop protein-based targets that can be used to diagnose and treat disease. SoyMeds' lead candidates include thyroglobulin and autoimmune (MS and MG) antigens.

Synapse Analytical Labs develops biomarker preparations and customized assays for the determination of medication compliance and antibiotic resistance. Synapse also provides testing services and reporting for medication compliance in clinical trials.

Tavros Therapeutics is developing novel therapeutics for cancer by using functional genomics to understand drug biology.

Vizma Life Sciences develops next-generation molecular imaging and chemical analysis solutions.

Zinfandel Pharmaceuticals uses pharmacogenetics to improve prediction of risk for Alzheimer’s disease and facilitate the development of effective therapies.