Chemical Synthesis

A1 BioChem Labs offers chemistry services to universities, pharma, agrochemical and biotech industries. Services include custom synthesis of APIs and novel compounds, catalog compound services, route screening, lead optimization and chemical sourcing.

Alcami provides contract drug and biologics development and manufacturing services, including formulation development, analytical chemistry, API, solid dose and parenteral drug manufacturing for both clinical and commercial markets.

Array BioPharma discovers, develops and commercializes targeted, small-molecule drugs to treat cancer.

Asymchem offers CMC and CDMO services, focused on developing processes for late-phase to commercial APIs and HPAPIs, and small-molecule manufacturing and development. Asymchem is USFDA- and TGA-inspected.

Biogen discovers, develops and manufactures therapies for serious neurological diseases. This site houses oral solid dose and anti-sense oligonucleotide production, packaging and fill/finish operations, as well as a Global Business Services center.

Boragen is developing a synthetic chemistry platform that leverages the unique characteristics of boron to address life science needs in crop protection and animal health.

Cambrex offers development, analytical services and manufacturing of APIs and small molecule drugs. Its Durham site provides drug substance development and manufacturing, as well as analytical services and microbiology testing services.

ChemoGenics BioPharma provides collaborative drug discovery, bioanalytical, formulation and scale-up services. Capabilities include medicinal chemistry, DMPK, bioinformatics and preclinical models in cancer, inflammation and metabolic diseases.

CiVentiChem provides contract R&D and manufacturing services including medicinal chemistry, process R&D, scale-up synthesis and manufacturing of intermediates and Regulatory Starting Materials (RSM).

Creative PEGWorks manufactures and supplies advanced functional polymer products for research. Main product lines include PEG, polysaccharides, biodegradable polyester, copolymers and PEGylation service.

EpiCypher develops and manufactures novel products and tools for epigenetics and chromatin biology, focused on enabling drug discovery research and development.

Exela Pharma Sciences develops, manufactures and markets sterile injectable pharmaceuticals and provides contract manufacturing services. The Lenoir site is a cGMP-compliant sterile manufacturing facility.

Glycan Therapeutics offers synthetic carbohydrates of various lengths to aid researchers investigating multiple therapeutic areas. Glycan also offers custom synthesis and array analysis of heparan and chondroitin sulfate oligosaccharides derivatives.

HeiQ ChemTex develops and manufactures specialty chemicals for the carpet, textiles, paper, coated fabrics, oil field recovery and specialty surfactants industries. Its product Bac-Shield contains a natural microbial extracted from snow crab shells.

Icagen partners with global pharmaceutical and biotech companies to generate high-quality, advanced leads, with expertise in kinases, GPCR’s, ion channels and transporters.

Intarcia Therapeutics is developing a continuous subcutaneous delivery system for the treatment of Type 2 diabetes. The RTP location discovers and develops peptide therapeutic drugs to augment Intarcia's drug delivery platform.

Madera Therapeutics is developing small molecule anti-cancer agents that function via an initial disruption of mitochondrial function ultimately leading to an immune response against the cancer.

MedKoo Biosciences supplies biochemical reagents, specializing in small molecule research-used medicines (i.e. non-human-use drugs).

MonomerChem provides contract drug development services, including custom synthesis, medicinal chemistry, lead optimization and synthesis of reference standards and metabolites.

NIRvana Sciences is commercializing red and near-infrared fluorescent dyes for use in diagnostics and imaging applications.

NovaTarg discovers and develops new medicines to treat metabolic diseases and cancer.

NSI Lab Solutions develops, manufactures and certifies reference materials, proficiency tests and customized standards for environmental, chemical, food, pharamceutical, cannabis, municipal and analytical testing laboratories.

OpAns provides analytical services to support discovery, preclinical, toxicology and clinical studies.

Phytonix develops and commercializes technologies and production processes that photosynthetically convert CO2, with solar energy and water, into low-cost solar chemicals and fuels such as butanols and octonols.

QCL offers both large and small molecule analytical and microbiological testing, including raw-materials and finished-products, stability storage & testing, method development/validation, formulation development and clinical manufacturing/packaging.

Raybow USA (formerly PharmAgra Labs) conducts contract R&D in organic and analytical chemistry for industries including pharma/biotech and electronics. Raybow offers cGMP services including development of APIs for clinical trials and manufacturing.

RTI, an independent, nonprofit institute, offers scientific and technical expertise in social and laboratory sciences, engineering and international development to government and commercial clients worldwide.

SDA BIO develops and manufactures biological reagents, pharmaceutical materials, and vaccine adjuvants. SDA BIO also provides analytical and process support for biologics manufacturing.

SenGenix develops point-of-care blood diagnostic tests using bioengineered fluorescently-responsive sensors. Testing is done with a finger stick and results are available immediately.

Statera develops innovative environmental monitoring products and provides environmental technology consulting services.

Symmetry Biosciences provides contract research, specialized chemistry services and bioanalytic services to the biotech, pharmaceutical, medical device, agrochemical and fine chemical industries.

Synthonix designs, manufactures and markets molecules to aid in drug discovery.

Verdesian Life Sciences' lab in RTP focuses on the exploration of emerging and disruptive technologies to improve plant nutrient use efficacy, agriculture productivity and environmental sustainability.