Combinatorial, Medicinal or Protein Chemistry

NCBiotech Company Directory is a comprehensive listing of North Carolina's life science industry New search

Company Title Company Description City
A1 BioChem Labs LLC

A1 BioChem Labs offers chemistry services to universities, pharma, agrochemical and biotech industries. Services include custom synthesis of APIs and novel compounds, catalog compound services, route screening, lead optimization and chemical sourcing.

Wilmington
Aerie Pharmaceuticals Inc.

Aerie Pharmaceuticals discovers, develops and commercializes first-in-class therapies for the treatment of patients with glaucoma.

Durham
Affinergy LLC

Affinergy develops peptide-based technologies, including diagnostic products, research tools and therapeutic drug monitoring products for use by clinicians and researchers.

Morrisville
Agile Sciences Inc.

Agile Sciences is developing a technology for the treatment of antibiotic-resistant, life-threatening infections.

Raleigh
Ajinomoto North America

Ajinomoto North America manufactures pharmaceutical-grade amino acids and custom-blended amino acid mixtures.

Raleigh
Array BioPharma Inc.

Array BioPharma discovers, develops and commercializes targeted, small-molecule drugs to treat cancer.

Morrisville
Asinex

Asinex designs small-molecule libraries and provides lead optimization, custom synthesis and other chemistry services. The Winston-Salem location is the company's U.S. headquarters.

Winston-Salem
Attagene Inc.

Attagene has developed a pathway profiling technology to evaluate the impact of pharmaceuticals and environmental chemicals on over 100 transcription factors and 48 nuclear receptors.

Morrisville
Bent Creek Institute Inc.

Bent Creek Institute is a 501(c)3 non-profit botanical research and economic development organization serving primarily North Carolina-based natural products companies seeking to innovate botanical wellness solutions.

Asheville
BindusChem LLC

BindusChem offers contract drug discovery and process chemistry projects for clients, synthesis of small molecules for SAR study, focused arrays and scaffolds, as well as chemical development, route scouting, process optimization and validation.

Research Triangle Park
BioAgilytix Labs Inc.

BioAgilytix is a bioanalytical lab specializing in large-molecule bioanalysis, offering PK, immunogenicity, biomarkers and cell-based assays in support of the development and release testing of biologics and small-molecule therapeutics.

Durham
BioCytics Inc.

BioCytics researches and develops personalized cellular immunotherapy cancer therapies with the latest technology and equipment. BioCytics also offers contract R&D and is incubated within the Carolina BioOncology Institute.

Huntersville
Blue Ridge Institute for Medical Research

Blue Ridge Institute for Medical Research (BRIMR) researches small-molecule inhibitors of protein kinases and targeted cancer therapies. BRIMR also generates an annual ranking of NIH funding for U.S. medical schools and their departments.

Horse Shoe
Boragen Inc.

Boragen is developing a synthetic chemistry platform that leverages the unique characteristics of boron to address life science needs in crop protection and animal health.

Research Triangle Park
Bright Path Pharmaceuticals LLC

Bright Path Pharmaceuticals develops chemical reactor technology for pharmaceutical manufacturing.

Kannapolis
Cambrex

Cambrex offers development, analytical services and manufacturing of APIs and small molecule drugs. Its Durham site provides drug substance development and manufacturing, as well as analytical services and microbiology testing services.

Durham
Cambrex High Point

Cambrex High Point develops and manufactures small-molecule APIs and intermediates for Phase I through III clinical trials. It offers custom organic synthesis, process development, analytical development and cGMP manufacturing services.

High Point
ChemoGenics Biopharma LLC

ChemoGenics BioPharma provides collaborative drug discovery, bioanalytical, formulation and scale-up services. Capabilities include medicinal chemistry, DMPK, bioinformatics and preclinical models in cancer, inflammation and metabolic diseases.

Research Triangle Park
Cloud Pharmaceuticals Inc.

Cloud Pharmaceuticals designs and develops novel drug molecules using computational design for a wide range of therapeutic areas including cancer, inflammation, CNS disorders and rare diseases.

Research Triangle Park
Creative PEGWorks

Creative PEGWorks manufactures and supplies advanced functional polymer products for research. Main product lines include PEG, polysaccharides, biodegradable polyester, copolymers and PEGylation service.

Research Triangle Park
Curl Bio LLC

Curl Bio develops drugs for the interrelated set of disorders involving Type 2 diabetes, obesity, fatty liver disease, metabolic syndrome and associated complications.

Durham
Dina Pharmaceuticals Inc.

Dina Pharmaceuticals is developing a treatment for Levodopa-Induced Dyskinesia (LID) associated with Parkinson’s disease.

Raleigh
DSK Biopharma Inc.

DSK Biopharma provides custom synthesis and medicinal chemistry services. DSK develops and supplies fine chemicals, APIs and intermediates, scaffolds, inhibitors, amino acids, carbohydrates, peptides, coupling reagents and other compounds.

Morrisville
ENCO Pharmaceutical Development Inc.

ENCO Pharmaceutical Development Inc. (EPDI) provides analytical services, comprehensive stability storage and related testing, as well as a product and formulation development services.

Cary
Enzerna Biosciences Inc.

Enzerna Biosciences is developing a gene therapy approach, called ASRE, for the treatment nucleotide expansion disorders, such as Huntington’s Disease and Myotonic Dystrophy, which cannot be addressed using current CRISPR/Cas technology.

Chapel Hill
EpiCypher Inc.

EpiCypher develops and manufactures novel products and tools for epigenetics and chromatin biology, focused on enabling drug discovery research and development.

Durham
FLAG Therapeutics Inc.

FLAG Therapeutics develops cancer therapeutics using new classes of small molecules which have selective dual activity: antiangiogenesis and chemotherapeutic.

Raleigh
Glycan Therapeutics Inc.

Glycan Therapeutics offers synthetic carbohydrates of various lengths to aid researchers investigating multiple therapeutic areas. Glycan also offers custom synthesis and array analysis of heparan and chondroitin sulfate oligosaccharides derivatives.

Raleigh
HDH Pharma Inc.

HDH Pharma offers contract chemistry research services to the biopharma industry, including medicinal and process chemistry; organic synthesis; CMC analytical and bioanalytical services; and API intermediate, inhibitor and screening compound provision.

Morrisville
Heteroz LLC

Heteroz supplies building blocks and screening compounds for research and development and provides custom synthesis of organic and inorganic compounds for the chemical, pharmaceutical and agrochemical industries.

Raleigh
Icagen Inc.

Icagen partners with global pharmaceutical and biotech companies to generate high-quality, advanced leads, with expertise in kinases, GPCR’s, ion channels and transporters.

Durham
Intarcia Therapeutics Inc.

Intarcia Therapeutics is developing a continuous subcutaneous delivery system for the treatment of Type 2 diabetes. The RTP location discovers and develops peptide therapeutic drugs to augment Intarcia's drug delivery platform.

Research Triangle Park
IProbeLabs Inc.

IProbeLabs offers medicinal chemistry services, including design, structure optimization, structural-activity relationship (SAR) analysis and preclinical studies of active pharmaceutical ingredients and drug leads.

Research Triangle Park
Jericho Sciences LLC

Jericho Sciences is developing antiviral therapeutics and corresponding personalized diagnostics for the clinical management of HIV-1 infection.

Research Triangle Park
LigaTrap Technologies

LigaTrap Technologies provides proprietary affinity chromatography resins and supporting products. LigaTrap also provides custom services for process development, small batch cell culture, scale up purification and assays.

Durham
Madera Therapeutics LLC

Madera Therapeutics is developing small molecule anti-cancer agents that function via an initial disruption of mitochondrial function ultimately leading to an immune response against the cancer.

Cary
MedKoo Biosciences Inc.

MedKoo supplies drug substances and bioactive molecules for life-science and biomedical study,

Morrisville
MonomerChem Inc.

MonomerChem provides contract drug development services, including custom synthesis, medicinal chemistry, lead optimization and synthesis of reference standards and metabolites.

Durham
NanoMedica LLC

NanoMedica provides ultrasensitive detection reagents and nanotechnology-based drug discovery services and tools to biopharmaceutical companies as well as DNA and RNA sequencing services.

Winston-Salem
NovaTarg Inc.

NovaTarg discovers and develops new medicines to treat metabolic diseases and cancer.

Research Triangle Park
Novex Innovations LLC

Novex Innovations is a contract development and manufacturing organization (CDMO) supporting small and startup life science companies in the development of their products, from concept through manufacturing and commercialization.

Winston-Salem
Olsen Pharmaceutical Consulting LLC

Olsen Pharmaceutical Consulting provides expertise in chemistry, manufacturing, control, and regulatory issues to the pharma industry. Focus areas include analytical development, quality control, impurity control strategies and genotoxic impurities.

Wake Forest
Parion Sciences Inc.

Parion Sciences develops therapies to treat defects of the innate mucosal defense system in respiratory and ophthalmology diseases.

Durham
Pathfinder Pharmaceuticals Inc.

Pathfinder Pharmaceuticals specializes in early stage drug discovery with a focus on cancer therapy.

Durham
PharmAgra Labs Inc.

PharmAgra Labs conducts contract research and development in organic chemistry for industries including pharma/biotech and electronics. PharmAgra also offers cGMP services including clinical trial materials supply and low-volume API manufacturing.

Brevard
Piedmont Animal Health Inc.

Piedmont Animal Health develops, licenses and markets animal health therapeutics with a focus on major companion animal categories.

Greensboro
R&S Chemicals Inc.

R&S Chemicals offers custom synthesis of organic chemicals, stable isotope labeled organic molecules and APIs, impurities identification and synthesis, medicinal chemistry and drug discovery services.

Kannapolis
Recipharm Laboratories Inc.

Recipharm provides product development and manufacturing services covering inhalation products, oral solids, steriles, semi-solids and API, as well as analytical services.

Morrisville
Rescindo Therapeutics Inc.

Rescindo Therapeutics discovers novel therapeutic targets and drugs for human genetic disorders based on humanized zebrafish in vivo modeling.

Durham
Ribometrix Inc.

Ribometrix is a platform therapeutics company discovering small-molecule drugs that target functional RNA structures to create new avenues to treat human disease.

Durham
RTI International

RTI, an independent, nonprofit institute, offers scientific and technical expertise in social and laboratory sciences, engineering and international development to government and commercial clients worldwide.

Research Triangle Park
SeaTox Research Inc.

SeaTox Research develops bioassays for the detection of marine toxins and conducts pharmaceutical development through bioprospecting.

Wilmington
SenGenix Inc.

SenGenix develops point-of-care blood diagnostic tests using bioengineered fluorescently-responsive sensors. Testing is done with a finger stick and results are available immediately.

Durham
Spirovation Inc.

Spirovation is a specialty CRO with a focus on the development of breakthrough drugs in respiratory medicine. Spirovation is non-profit, UNC-affiliated entity.

Chapel Hill
Sterling Pharma USA LLC

Sterling Pharma Solutions provides contract small molecule API development and manufacturing services to the global pharmaceutical industry.

Cary
Symmetry Biosciences Inc.

Symmetry Biosciences provides contract research, specialized chemistry services and bioanalytic services to the biotech, pharmaceutical, medical device, agrochemical and fine chemical industries.

Raleigh
Ten63 Therapeutics Inc.

Ten63 Therapeutics uses computational chemistry and AI to screen trillions of molecules to discover new therapeutics.

Chapel Hill
Thermo Fisher Scientific (Greenville)

Thermo Fisher’s Pharma Services Division offers drug development and manufacturing. Its Greenville site manufactures sterile injectables, tablets and capsules. It also offers stability storage and testing, and API and large-molecule development.

Greenville
Trana Discovery Inc.

Trana Discovery provides an anti-infective discovery platform that enables its partners to identify novel treatments that possess pathogen-focused spectrums of activity for bacterial, viral and fungal infectious diseases in crops, animals and humans.

Cary
Vijaya Pharmaceuticals LLC

Vijaya Pharmaceuticals provides medicinal and synthetic organic chemistry services to the pharmaceutical and allied industries.

Research Triangle Park