Drug Delivery Technologies

NCBiotech Company Directory is a comprehensive listing of North Carolina's life science industry New search

Company Title Company Description City
Drug Development Consulting, Small Molecule Bioanalysis and Pharmacokinetics Xyzagen Inc.

Xyzagen is a full service nonclinical discovery bioanalytical and in vivo pharmacokinetics and pharmacology research lab. Xyzagen offers drug development consulting, clinical pharmacokinetics and GLP toxicokinetics.

Pittsboro
21MedTech

21MedTech develops and offers advanced, proprietary, bioresorbable resins for controlled release drug delivery, regenerative devices and 3D manufacturing.

Holly Springs
AccuBeing LLC

AccuBeing creates three-dimensional cancer organoids from patients' cancer cells, which are used to test novel drug therapies, transcriptomic and epigenetic analyses. Results are used to match the patient with personalized clinical trials.

Raleigh
Achelios Therapeutics Inc.

Achelios Therapeutics develops novel topical therapeutics for the treatment of inflammatory pain, including migraine and temporomandibular joint disorder pain.

Durham
Adámas Nanotechnologies Inc.

Adámas Nanotechnologies develops and produces fluorescent nanodiamond particles for life science, medical and industrial applications, including life science research, drug delivery, bioimaging, anti-counterfeiting, oil additives and cosmetics.

Raleigh
Adroit Pharmaceutical Development LLC

Adroit Pharmaceutical Development identifies new and improved formulations and process technologies. Its primary focus is on inhalation and dermatological product development.

Durham
Advanced Chemotherapy Technologies Inc.

Advanced Chemotherapy Technologies, a UNC startup, has developed a novel device for infusing chemotherapies directly into poorly-vascularized pancreatic tumors.

Raleigh
Aerie Pharmaceuticals Inc.

Aerie Pharmaceuticals discovers, develops and commercializes first-in-class therapies for the treatment of patients with glaucoma.

Durham
Aestas Pharma Inc.

Asetas Pharma develops novel diagnostic imaging and disease-modifying therapeutic agents to enable the early treatment and reversal of Alzheimer’s and Parkinson’s disease when clinical signs are not yet pronounced.

Lewisville
Affinergy LLC

Affinergy develops peptide-based technologies, including diagnostic products, research tools and therapeutic drug monitoring products for use by clinicians and researchers.

Morrisville
Alpha Nano Tech LLC

Alpha Nano Tech provides nanoparticle and exosome characterization services.

Research Triangle Park
AnelleO

AnelleO is developing a 3D-printed intravaginal ring that can be used for treating infertility and a wide range of other women's health conditions.

Chapel Hill
Aniluxx Biotechnology Inc.

Aniluxx Biotechnology translates human therapies to dogs, cats and horses to treat itching and pain.

Raleigh
Apeirolux Pharmaceutical Inc.

Apeirolux Pharmaceutical is developing a tumor-cell selective topical skin cream for the treatment of skin cancer.

Fuquay Varina
Applied Catheter Technologies Inc.

Applied Catheter Technologies develops drug-coated medical devices that inhibit scar formation. The company's first products under development are catheters for male urethral stricture and devices that inhibit abdominal adhesions.

Winston-Salem
Applied LifeSciences & Systems Poultry Inc.

Applied LifeSciences & Systems Poultry develops automated bio-system solutions for detecting, targeting and delivering vaccines to poultry. ALS-S technology aims to reduce the need for antibiotics by improving vaccination delivery.

Morrisville
Arcato Laboratories Inc.

Arcato Laboratories develops specialty oral healthcare products including treatment for pain and discomfort from orthodontic appliances and post-surgical tooth extraction.

Greenville
Ardeal Pharma Inc.

Ardeal Pharma is a virtual pharma company developing patented stabilized sulforaphane for the dermal pharmaceutical and cosmetic markets.

Brevard
Ardeal Research Institute

Ardeal Research Institute is a non-profit organization that develops drug discovery capabilities of the natural resources in Western North Carolina. The Institute has collaboration agreements in place with Brevard College and the N.C. Arboretum.

Brevard
Aruna Bio

Aruna Bio develops neural exosomes for the treatment of neurodegenerative diseases.

Raleigh
Avior Inc.

Avior is developing a nanoparticle-based drug delivery technology to deliver lipophilic drugs with high bioavailability. It is testing its technology using a molecule for the treatment of pruritus in chronic kidney disease.

Durham
Aweve LLC

Aweve designs and manufactures cosmeceuticals that utilize nanoparticles for the delivery of retinol, ascorbic acid and kojic acid to address wrinkles, lines, age spots and elasticity in skin.

Raleigh
Banner Life Sciences LLC

Banner Life Sciences develops formulation technologies (gelcaps, tablets and sterile injectables) and licenses and markets prescription, over-the-counter and nutritional products.

High Point
BD Technologies and Innovation

BD Technologies and Innovation develops technologies for parenteral drug delivery, advanced diagnostics, smart medical devices and genomic research and supports external innovation. The RTP site is BD's corporate technology R&D and innovation center.

Research Triangle Park
Bent Creek Institute Inc.

Bent Creek Institute is a 501(c)3 non-profit botanical research and economic development organization serving primarily North Carolina-based natural products companies seeking to innovate botanical wellness solutions.

Asheville
BioCytics Inc.

BioCytics researches and develops personalized cellular immunotherapy cancer therapies with the latest technology and equipment. BioCytics also offers contract R&D and is incubated within the Carolina BioOncology Institute.

Huntersville
BioDelivery Sciences International Inc.

BioDelivery Sciences is a specialty pharmaceutical company with a focus in the areas of pain management and addiction. The company's lead products utilize a buccal film delivery system.

Raleigh
BioKier Inc.

BioKier develops proprietary adjuvant treatments for diabetes and related disorders. BioKier has identified a therapeutic opportunity based on gastric bypass surgery and is developing a novel treatment for diabetes.

Chapel Hill
BioMarck Pharmaceuticals Ltd.

BioMarck develops drugs to treat pulmonary diseases and disorders, such as chronic obstructive pulmonary disease, ARDS, cystic fibrosis and lung cancer.

Durham
Brain Neurotherapy Bio Inc.

Brain Neurotherapy Bio is developing delivery technologies for viral vector-based gene therapies to treat adult and pediatric central nervous system disorders.

Research Triangle Park
Capture Pharmaceuticals Inc.

Capture Pharmaceuticals develops oral treatments for removing toxic or radioactive metals in contaminated individuals.

Chapel Hill
Catalent Pharma Solutions LLC

Catalent provides drug development and manufacturing services for the pharma, biotech and consumer sectors. Core offerings include biologics, parenterals, oral solids, softgel, inhalation, clinical supply services and analytical services.

Morrisville
Charles River Laboratories (Morrisville)

Charles River Laboratories' Oncology Center of Excellence provides in vivo and in vitro oncology and immuno-oncology research services.

Morrisville
Chesson Laboratory Associates Inc.

Chesson Labs develops prescription and over-the-counter polymer-based medical products for wound care and skin and nail care products.

Durham
Chimerix Inc.

Chimerix discovers, develops and commercializes broad spectrum antivirals for the prevention and treatment of life-threatening viral infections.

Durham
Cloud Pharmaceuticals Inc.

Cloud Pharmaceuticals designs and develops novel drug molecules using computational design for a wide range of therapeutic areas including cancer, inflammation, CNS disorders and rare diseases.

Research Triangle Park
Cognosci Inc.

Cognosci develops neurorestorative therapies for Alzheimer's disease, multiple sclerosis, traumatic brain injury, nerve crush and other disease and trauma indications.

Durham
Concentrx Pharmaceuticals Inc.

Concentrx develops inhaled prescription products for asthma and COPD, including a unit dose disposable dry powder inhaler.

Durham
Daily Manufacturing Inc.

Daily Manufacturing manufactures vitamins, minerals and herbals. The company also manufactures products for other supplement companies with their own brand names.

Rockwell
DaVINCI Biomedical Research Products Inc.

DaVINCI Biomedical Research is an AAALAC-accredited contract lab that performs GLP and non-GLP preclinical animal studies. DaVINCI specializes in regenerative medicine, cardiovascular, orthopedic and medical device applications.

Garner
Dharma Laboratories LLC

Dharma Laboratories offers scientific, regulatory and formulation development expertise to develop specialty and generic pharmaceutical products. The company develops novel dosage forms and proof-of-concept formulations for early clinical studies.

Morrisville
Diabetic Health Inc.

Diabetic Health develops coatings to improve the longevity and performance of continuous glucose monitoring sensors (CGM) and insulin infusion sets used in diabetes management.

Research Triangle Park
Dignify Therapeutics LLC

Dignify Therapeutics develops bladder and bowel drug therapies for spinal cord-injured, multiple sclerosis and similar patient populations with voiding dysfunction.

Research Triangle Park
Dualogics LLC

Dualogics researches and develops bispecific antibody products based on their proprietary OrthoMab platform.

Chapel Hill
Entegrion Inc.

Entegrion develops biologic and medical device technologies to enhance the safety and availability of the human blood supply. The company also provides blood supply-related contract R&D services to the U.S. Department of Defense.

Durham
Exodos Life Science Partners

Exodos Life Sciences advances product concepts through the 505(b)(2) process to early clinical proof-of-principle and sale. Exodus specializes in topical formulations for the treatment of Raynaud's Syndrome, cold sores and nail fungus.

Chapel Hill
Falcon Therapeutics Inc.

Falcon Therapeutics develops gene-modified cell therapy technology which can turn a patient's own skin cells into "Trilogy Cells" that seek out and destroy cancer cells without expected side effects.

Durham
Fortovia Therapeutics Inc.

Fortovia Therapeutics develops and commercializes oncology treatments and products for treating chemotherapy or radiotherapy side effects.

Raleigh
Fresenius Kabi USA LLC

Fresenius Kabi manufactures medical devices and sterile injection- and infusion-based drug-delivery products.

Wilson
Genebiology Inc.

GeneBiology identifies, patents and develops new parenteral formulations of approved drugs for unmet medical needs using the 505b2 regulatory pathway.

Research Triangle Park
Genencine Therapeutics LLC

Genencine Therapeutics develops mRNA vaccines for the prevention and treatment of cancer, viral diseases and autoimmune diseases, as well as mRNA therapeutic drugs for genetic diseases.

Durham
Gilero

Gilero provides design, development and contract manufacturing services in the medical device and drug delivery markets.

Morrisville
Glenmark Pharmaceuticals Inc., USA

Glenmark Pharmaceuticals discovers small-molecule drugs and biologics in the areas of oncology, respiratory disease and dermatology, and manufactures and distributes APIs and generics. The Monroe site manufactures oral solids, injectables and topicals.

Monroe
Gyrus Pharmaceuticals Inc.

Gyrus Pharmaceuticals is developing treatments for serious diseases of the central nervous system using proprietary therapeutic agents and nanoparticles for noninvasive delivery to the CNS.

Chapel Hill
Hammock Pharmaceuticals Inc.

Hammock Pharmaceuticals licenses and develops women's health and urology products. It is developing a metronidazole and clindamycin vaginal gel for the treatment of bacterial vaginosis, and a urology product for the treatment of radiation cystitis.

Charlotte
HDH Pharma Inc.

HDH Pharma offers contract chemistry research services to the biopharma industry, including medicinal and process chemistry; organic synthesis; CMC analytical and bioanalytical services; and API intermediate, inhibitor and screening compound provision.

Morrisville
High Point Clinical Trials Center

High Point Clinical Trials Center conducts phase one and two clinical research studies to test emerging drugs for pharmaceutical companies.

High Point
IMMvention Therapeutix Inc.

IMMvention develops novel therapies to fulfill unmet needs of patients with rare and common inflammatory diseases and cancer.

Durham
Indicus Pharma LLC

Indicus develops generic formulations in oral solid dosage forms, parenterals and ophthalmics. Products are manufactured at a partner facility in India.

Raleigh
Inhalon Biopharma Inc.

Inhalon Biopharma is developing monoclonal antibodies (mAb) using technology that enables trapping of pathogens in mucus secretions for treating diseases of the respiratory tract.

Carrboro
Initos Pharmaceuticals LLC

Initos Pharmaceuticals is developing a platform delivery technology for nucleic acid therapeutics to develop agents to enhance intracellular delivery of oligonucleotides, peptides and proteins.

Chapel Hill
Intarcia Therapeutics Inc.

Intarcia Therapeutics is developing a continuous subcutaneous delivery system for the treatment of Type 2 diabetes. The RTP location discovers and develops peptide therapeutic drugs to augment Intarcia's drug delivery platform.

Research Triangle Park
Isosceles Pharmaceuticals Inc.

Isosceles Pharmaceuticals is developing parenteral products for delivery of synthetic CBD to treat pain.

Wilmington
Jericho Sciences LLC

Jericho Sciences is developing antiviral therapeutics and corresponding personalized diagnostics for the clinical management of HIV-1 infection.

Research Triangle Park
Kitty Hawk Biosciences Inc.

Kitty Hawk Biosciences is developing enabling technologies for difficult-to-transfect cells to reduce the cost and complexity of ex-vivo cell manipulations for applications in research and clinical settings.

Cary
Knightpoint Group LLC

Knightpoint Group offers contract development and manufacturing services, specializing in parenteral and respiratory drug delivery products. Knightpoint Group is also developing a platform capsule inhaler technology for large doses.

Cary
Lindy Biosciences Inc.

Lindy Biosciences develops protein therapeutic formulations for non-standard formulations such as suspension formulations (for high-concentration delivery of antibodies), encapsulation (for sustained/controlled release) or dry powder pulmonary delivery.

Research Triangle Park
Liquidia Technologies Inc.

Liquidia Technologies develops and commercializes human therapeutics for the treatment of pulmonary arterial hypertension and post-operative pain using its proprietary particle engineering technology.

Morrisville
Locus Biosciences Inc.

Locus Biosciences is developing CRISPR-engineered bacteriophage (“crPhage”) products that kill target bacteria by irreversibly destroying their DNA while leaving the many species of beneficial bacteria in the body unharmed.

Morrisville
MAA Laboratories Inc.

MAA Laboratories develops new drug products by nanoformulating currently marketed drugs with meaningful clinical benefits. The company’s NanoCont technology requires small clinical trials for the new product regulatory approval through 505(b)(2) pathway.

Durham
Mayne Pharma USA

Mayne Pharma manufactures oral and topical dosage branded and generic pharmaceuticals. Mayne Pharma also provides contract development and manufacturing services. Mayne Pharma's U.S. headquarters is in Raleigh.

Raleigh
Mayne Pharma USA (Greenville)

Mayne Pharma manufactures branded and generic oral solid dose pharmaceuticals. The Greenville site is Mayne Pharma’s U.S. development and manufacturing facility.

Greenville
MedKoo Biosciences Inc.

MedKoo supplies drug substances and bioactive molecules for life-science and biomedical study,

Morrisville
Micell Technologies Inc.

Micell Technologies develops combination-product therapies for interventional cardiology. Micell markets MiStent, a drug-eluting stent, in Europe and certain other regions.

Durham
Micropore Technologies Inc.

Micropore Technologies provides particle emulsification and encapsulation equipment, manufacturing and consulting for industries including pharmaceuticals, nutraceuticals, agrochemicals and food products.

Morrisville
ML Bio Solutions Inc.

ML Bio Solutions is developing BBP-418, an oral treatment for patients with LGMD2i.

Charlotte
Mucodel Pharma LLC

Mucodel Pharma develops technologies for enhancing drug delivery via mucosal routes of administration. Its first candidate is a buccal gel for pain treatment and emergency treatment of opioid overdose.

Greensboro
Mucommune LLC

Mucommune researches improved protection against infectious diseases transmitted at mucosal surfaces. Mucommune's current focus is a method to prevent sexually transmitted infections using monoclonal antibodies encapsulated in a polymeric capsule.

Carrboro
Nitta Gelatin NA Inc.

Nitta Gelatin manufactures food, pharmaceutical and technical gelatin and is the maker of beMatrix Low Endotoxin Gelatin. beMatrix is used in the fields of regenerative medicine, medical devices and scientific research.

Morrisville
Novan Inc.

Novan develops therapies for dermatological conditions, women's health and gastrointestinal disease using its nitric oxide-releasing technology.

Morrisville
Novex Innovations LLC

Novex Innovations is a contract development and manufacturing organization (CDMO) supporting small and startup life science companies in the development of their products, from concept through manufacturing and commercialization.

Winston-Salem
Nu Chemie LLC

NuChemie is developing and commercializing nanomaterials for drug delivery and water soluble and traceable bioconjugation reagents. NuChemie also provides custom synthesis services.

Charlotte
Nufabrx

Textile-Based Delivery develops and manufactures fabrics that integrate controlled release matrices, offering topical and transdermal dosing of active ingredients.

Conover
OncoTrap Inc.

OncoTrap is developing a nucleic acid delivery platform for accommodating nucleic acid-based therapeutics, designed to deliver therapeutic genes to tumor sites.

Research Triangle Park
Oriel Therapeutics Inc., a Sandoz company (Durham)

Oriel operates as Sandoz' product development center, which develops respiratory products as generic alternatives to patented drugs for asthma and COPD. It also develops and commercializes pre-metered unit and multi-dose dry powder delivery systems.

Durham
Osmotica Pharmaceutical Corp.

Osmotica Pharmaceutical specializes in drug-delivery technologies and neurology-based therapies, including a treatment for Parkinson's disease.

Wilmington
Parion Sciences Inc.

Parion Sciences develops therapies to treat defects of the innate mucosal defense system in respiratory and ophthalmology diseases.

Durham
Piedmont Animal Health Inc.

Piedmont Animal Health develops, licenses and markets animal health therapeutics with a focus on major companion animal categories.

Greensboro
Plakous Therapeutics LLC

Plakous Therapeutics is developing biotherapeutics from post-delivery placenta to promote regenerative healing for diseases including osteoarthritis, necrotizing enterocolitis, wound healing and tissue engraftment.

Winston-Salem
Polyzen Inc.

Polyzen is a contract manufacturer that designs, develops, and manufactures polymer-based medical devices. Polyzen has polymer processing capabilities for prototyping and volume production.

Apex
Precision BioSciences Inc.

Precision BioSciences utilizes a proprietary genome editing method called ARCUS to treat cancers and genetic diseases, and enable the development of safer, more productive food sources.

Durham
Recipharm Laboratories Inc.

Recipharm provides product development and manufacturing services covering inhalation products, oral solids, steriles, semi-solids and API, as well as analytical services.

Morrisville
Rilento Pharma LLC

Rilento Pharma is an early stage drug delivery company developing non-addictive oral surgery pain management technologies that are synchronized with the biologic process of wound healing.

Raleigh
RTI International

RTI, an independent, nonprofit institute, offers scientific and technical expertise in social and laboratory sciences, engineering and international development to government and commercial clients worldwide.

Research Triangle Park
Sagent Pharmaceuticals

Sagent Pharmaceuticals develops, manufactures, packages and markets pharmaceutical products with an emphasis on injectables. Its Raleigh site produces sterile injectables and lyophilized formulations of biosimilars.

Raleigh
Satsuma Pharmaceuticals Inc.

Satsuma Pharmaceuticals is developing best-in-class intranasal drug products to address the significant unmet medical needs of acute migraine sufferers.

Durham
Shoaf Scientific Consultants Inc.

Shoaf Scientific Consultants provides research and development services in plant redox bioenergetics, antimicrobial surface technologies and molecular photochemical studies in singlet oxygen and superoxide-free radical anion as applied to aging.

Lexington
SiNON Therapeutics

SiNON is developing technology to treat neurological diseases by increasing the ability of drugs to cross the blood brain barrier (BBB).

Durham
Spirovation Inc.

Spirovation is a specialty CRO with a focus on the development of breakthrough drugs in respiratory medicine. Spirovation is non-profit, UNC-affiliated entity.

Chapel Hill
Sterling Pharma USA LLC

Sterling Pharma Solutions provides contract small molecule API development and manufacturing services to the global pharmaceutical industry.

Cary

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