Proteins and Enzymes

NCBiotech Company Directory is a comprehensive listing of North Carolina's life science industry New search

Company Title Company Description City
Invitrox Inc.

Invitrox provides GLP-compliant bioanalytical services for nonclinical and clinical drug development studies, with expertise in method development and validation, small and large molecules, sample analysis, metabolites, biomarkers and drug monitoring.

Research Triangle Park
North Carolina Central University - Biomanufacturing Research Institute and Technology Enterprise Center for Excellence

Biomanufacturing Research Institute & Technology Enterprise (BRITE) is hands-on education and training program at NC Central University that focuses on teaching the process of drug development.

Durham
3i-Nano

3i Nano develops point-of-care devices for disease diagnostics and protein detection.

Greensboro
AC Thera LLC

AC Thera is developing drugs to neutralize bacterial toxins for the treatment of diseases with high mortality.

Wake Forest
Aestas Pharma Inc.

Asetas Pharma develops novel diagnostic imaging and disease-modifying therapeutic agents to enable the early treatment and reversal of Alzheimer’s and Parkinson’s disease when clinical signs are not yet pronounced.

Lewisville
Affinergy LLC

Affinergy develops peptide-based technologies, including diagnostic products, research tools and therapeutic drug monitoring products for use by clinicians and researchers.

Morrisville
AgBiome Inc.

AgBiome uses its proprietary Genesis platform to collect, isolate and analyze microbes for use in the discovery and development of biologicals and traits for protecting crops, and is researching probiotic products to address swine gut health challenges.

Research Triangle Park
Alcami Corporation

Alcami provides contract drug and biologics development and manufacturing services, including formulation development, analytical chemistry, API, solid dose and parenteral drug manufacturing for both clinical and commercial markets.

Wilmington
Alcami Corporation (Durham)

Alcami provides contract drug and biologics development and manufacturing services, including formulation development, analytical chemistry, API, solid dose and parenteral drug manufacturing for clinical and commercial markets. Alcami's HQ is in Durham.

Durham
Alera Labs LLC

Alera Labs provides contract research analytical chemistry, in vitro toxicology, GLP analysis and preformulation services to pharmaceutical, biotech and medical device companies.

Durham
AskBio

AskBio develops protein- and cell-based therapies using a proprietary technology platform called Biological Nano Particles (BNP).

Research Triangle Park
Atrium Health Division of Therapeutic Research and Development

The Division of Therapeutic Research and Development at Atrium Health conducts clinical studies, patient-focused translational research and outcomes research.

Charlotte
Avazyme Inc.

Avazyme provides field and GLP laboratory testing for sectors including agchem, agbiotech, food and beverage producers and retailers, and brewers. Capabilities include mass spectrometry, immunochemistry, microbiology and molecular biology.

Durham
Avioq Inc.

Avioq develops and manufactures FDA-approved and CE-marked immunodiagnostic assays. Products include HIV and HTLV assays, recombinant proteins and synthetic peptides and labware supplies. Avioq also offers contract IVD development and manufacturing.

Research Triangle Park
Baebies Inc.

Baebies develops and delivers products and services based on digital microfluidics and other technology to advance newborn screening and pediatric testing worldwide.

Durham
BASF Agricultural Solutions

BASF's Agricultural Solutions division conducts seeds, traits and plant biotechnology research with a focus on yield and quality traits in major crops. Its RTP campus also houses a bee care center.

Morrisville
BioAgilytix Labs Inc.

BioAgilytix is a bioanalytical lab specializing in large-molecule bioanalysis, offering PK, immunogenicity, biomarkers and cell-based assays in support of the development and release testing of biologics and small-molecule therapeutics.

Durham
Biogen

Biogen discovers, develops and manufactures therapies for serious neurological diseases. Its Drug Substance Campus in RTP is home to biologics production and a patient services contact center.

Research Triangle Park
Biogen (Oral Solid Dose Facility)

Biogen discovers, develops and manufactures therapies for serious neurological diseases. This site houses oral solid dose and anti-sense oligonucleotide production, packaging and fill/finish operations, as well as a Global Business Services center.

Research Triangle Park
BioGreen Synergy Inc.

BioGreen Synergy manufactures, grows and provides algae-based products for use in alternative renewable energies, USDA, non-USDA and chemical markets.

Greensboro
BioMarck Pharmaceuticals Ltd.

BioMarck develops drugs to treat pulmonary diseases and disorders, such as chronic obstructive pulmonary disease, ARDS, cystic fibrosis and lung cancer.

Durham
BioMedomics Inc.

BioMedomics develops point-of-care (POC) diagnostics, with a focus on immunologically-based disease-specific tests and advanced quantitative POC platforms.

Durham
BioResource International Inc.

BioResource International (BRI) designs, develops and manufactures unique enzymes that help poultry and swine producers optimize animal nutrition and gut health.

Durham
Biotech Restorations LLC

Biotech Restorations formulates bioremediation products for the cleanup of petroleum and chlorinated hydrocarbons including gasoline and diesel, organochloride pesticides, PCBs and volatile organic chemicals in soil, sediment and groundwater.

Denver
BioVendor LLC

BioVendor develops, manufactures and sells biological reagents and research products, including enzyme-linked immunosorbent assay (ELISA) kits, antibodies, proteins and other molecules for life science research. This location is the U.S. headquarters.

Asheville
BioZyme Inc.

BioZyme develops and sells substrates for metalloproteinases (MMPs and ADAMs) which can be used in enzyme assays and other diagnostic tests.

Apex
Blue Ridge Institute for Medical Research

Blue Ridge Institute for Medical Research (BRIMR) researches small-molecule inhibitors of protein kinases and targeted cancer therapies.

Horse Shoe
CardioEphEx LLC

CardioEphEx develops therapeutics for cardiovascular disease and heart failure. The company's research focuses on cardioprotection by targeting the Ephrin/Eph receptor signaling pathway in the heart.

Bahama
Cellective BioTherapy Inc.

Cellective BioTherapy is developing cellular and monoclonal antibody-based platforms for treating cancers, autoimmunity and immunodeficiency.

Research Triangle Park
Cellex Inc.

Cellex develops, manufactures and markets diagnostic tests suitable for point-of-care use. These tests use a platform technology called Homogeneous Biochemiluminescence Assay (HBA), which enables assays that are highly sensitive and easy-to-use.

Research Triangle Park
Celplor LLC

Celplor provides molecular biology services, including stable cell line generation, Southern blot analysis, Western blot analysis, cDNA cloning and mouse tail genotyping.

Cary
Chaperone Therapeutics Inc.

Chaperone Therapeutics develops disease-modifying therapies for neurodegenerative and rare diseases caused by protein misfolding.

Chapel Hill
Charlotte Research Institute

The Charlotte Research Institute provides limited laboratory and office space to partner firms that are engaged in collaboration with its researchers.

Charlotte
CHD Technologies Inc.

CHD Technologies conducts chemical process R&D for agricultural and pharmaceutical intermediates. Competencies include distillation, rectification, crystallization, filtration and drying for batch and continuous chemical manufacturing processes.

Charlotte
Chirazyme

Chirazyme produces enzymes for stereospecific epoxidation intermediates in pharmaceutical synthesis.

Washington
Cognosci Inc.

Cognosci develops neurorestorative therapies for Alzheimer's disease, multiple sclerosis, traumatic brain injury, nerve crush and other disease and trauma indications.

Durham
Couragen Biopharmaceutics LLC

Couragen Biopharmaceutics develops gene and protein therapy products for preclinical and clinical use for the treatment of genetic and chronic diseases. Couragen also provides custom adeno-associated virus vectors as a tool for laboratory research.

Chapel Hill
Cygnus Technologies LLC

Cygnus Technologies develops products and services for the biopharma industry, including host cell protein ELISA kits, immunoassay reagents and custom development of antibodies and assays.

Southport
David H. Murdock Research Institute

The David H. Murdock Research Institute (DHMRI) provides collaborators with genomics, proteomics, metabolomics, light microscopy, NMR, clinical chemistry, cellular biology and immunology services. DHMRI focuses on human health, nutrition and agriculture.

Kannapolis
Dualogics LLC

Dualogics researches and develops bispecific antibody products based on their proprietary OrthoMab platform.

Chapel Hill
Enzyvant Inc.

Enzyvant develops therapeutics for treatment of rare diseases. Their focuses are RVT-802, an investigational tissue-based therapy for immune deficiency resulting from DiGeorge Anomaly, and RVT-801, an enzyme replacement therapy to treat Farber disease.

Durham
EpiCypher Inc.

EpiCypher develops and manufactures novel products and tools for epigenetics and chromatin biology, focused on enabling drug discovery research and development.

Research Triangle Park
Eppin Pharma Inc.

Eppin Pharma is developing a non-hormonal male oral contraceptive.

Durham
Eurofins Craft Technologies Inc.

Eurofins Craft Technologies provides analytical and method development services to measure nutritional components in blood, tissues, dietary supplements, food and animal feed.

Wilson
f(x) Immune Diagnostics Inc.

f(x) Immune Diagnostics provides advanced testing services to developers of immuno-therapeutics and vaccines using its proprietary technologies. The company's pipeline includes related clinical diagnostics, point-of-care and companion assays and systems.

Candler
FUJIFILM Diosynth Biotechnologies USA Inc.

Fujifilm Diosynth Biotechnologies provides biologics contract development and manufacturing. Services include cell line development, process and analytical development, clinical and commercial manufacturing and bioprocess research and development.

Morrisville
Gateway Research Park - North Campus

Gateway Research Park is a joint venture created by NC A&T State University and the University of North Carolina Greensboro to catalyze university research, innovation and economic development.

Browns Summit
GEM Tox Labs

GEM Tox Labs conducts research focused on cancer biotechnology, food safety and toxicology, with a special emphasis on cancer biomarker discovery and validation.

Greenville
General Biosystems Inc.

General Biosystems provides gene synthesis, molecular biology, and protein expression and purification services.

Morrisville
Golden LEAF Biomanufacturing Training and Education Center (BTEC)

BTEC provides hands-on education and training in bioprocessing and cGMP compliance to university students and industry employees. Faculty and staff also engage in process development activities in the 82,500 gsf facility.

Raleigh
Goldsboro Laboratories LLC

Goldsboro Laboratories develops and manufactures vaccines for the swine, poultry and cattle divisions of Goldsboro Milling Company.

Goldsboro
Grifols (Clayton)

Grifols' Clayton plant is the company's primary manufacturing facility, producing proteins to treat rare diseases including immune deficiencies and genetic emphysema.

Clayton
Huvepharma Inc.

Huvepharma manufactures Coccidiosis vaccines for in ovo and post-hatch vaccination of poultry.

Maxton
Ideal Health Biotechnology LLC

Ideal Health Biotechnology researches and develops dietary supplements made from plant-based compounds, including products derived from grape seed extract and algae for digestion, eye disease and diabetes.

Kannapolis
ImmunoReagents Inc.

ImmunoReagents manufactures primary and secondary polyclonal antibodies used in research and in vitro diagnostics for the pharmaceutical and veterinary markets.

Raleigh
Inanovate Inc.

Inanovate has developed a patented blood analysis system (the Bio-ID) for diagnostic tests. The first application of the Bio-ID is a new blood test to detect breast cancer recurrence at a stage when it may still be cured.

Raleigh
Indexus Biomedical LLC

Indexus Biomedical designs, develops and manufactures instrument systems, reagents and assays for in vitro diagnostics, initially focusing on the hematology and immunology markets.

Morrisville
Initos Pharmaceuticals LLC

Initos Pharmaceuticals is developing a platform delivery technology for nucleic acid therapeutics to develop agents to enhance intracellular delivery of oligonucleotides, peptides and proteins.

Chapel Hill
Innatrix Inc.

Innatrix is developing technology for the production of high-affinity, high specificity protein ligands to protein targets of interest. The company's applied focus is the agricultural sector.

Research Triangle Park
Innovate Biopharmaceuticals Inc.

Innovate Biopharmaceuticals develops novel medicines for autoimmune and inflammatory diseases with unmet needs, including drug candidates for celiac disease and NASH.

Raleigh
Insoma Bio Inc.

InSomaBio is developing recombinant, protein-based materials to solve problems in tissue engineering and regenerative medicine.

Durham
Isolere Bio Inc.

Isolere Bio is developing novel, non-chromatographic technologies for the purification of biologics such as antibodies, gene delivery vectors and personalized cell therapies.

Durham
Ivory Tower Science

Ivory Tower Science conducts research and educates students in fermentation sciences at its fermentation pilot plant.

Boone
Jericho Sciences LLC

Jericho Sciences is developing antiviral therapeutics and corresponding personalized diagnostics for the clinical management of HIV-1 infection.

Research Triangle Park
Kaio Therapy LLC

KAIO Therapy develops an immunotherapy technology to treat solid tumors.

Raleigh
KBI Biopharma Inc.

KBI Biopharma offers contract development and biopharmaceutical manufacturing services such as formulation, analytical method development, stability services, process development and recombinant protein API manufacturing. This site is KBI's headquarters.

Durham
KBI Biopharma Inc. (Process Development Facility)

KBI Biopharma offers contract development and biopharmaceutical manufacturing services. This site is KBI's process development facility.

Research Triangle Park
Keratin Biosciences Inc.

Keratin Biosciences advances regenerative medicine and drug delivery therapies for tissue injuries based on human-derived keratin technology platform. This site manufactures biomaterials for thermal burns, and bone, muscle and nerve regeneration.

Winston-Salem
KXTbio Inc.

KXTbio develops and commercializes reagents and assays for two major classes of drug targets, GTPases and G protein-coupled receptors.

Chapel Hill
LabCorp - Center for Molecular Biology and Pathology

LabCorp's Center for Molecular Biology and Pathology provides laboratory testing services. The company’s expertise is focused in diagnostic genetics, oncology and pathology.

Research Triangle Park
Laudiss Labs LLC

Laudiss Labs uses advanced proprietary platform technologies for quantitative DNA and protein testing of GMOs, foodborne pathogens and mycotoxins in food and feed.

Winston-Salem
LCMS Limited

LCMS provides LC/MS services for the identification and quantification of compounds in biological and environmental matrices. LCMS specializes in detecting cross contamination from food and drug manufacturing and also provides LC/MS training.

Durham
LeafPro LLC

LeafPro develops new technologies for producing naturally occurring proteins and coproducts from plant biomass.

Wilson
LifeEDIT

LifeEDIT, an AgBiome subsidiary, uses its bioinformatic pipeline to mine a microbial genome sequence database to develop gene editing systems. Systems are used in therapeutic and agriculture gene editing applications in-house and through partnerships.

Research Triangle Park
LigaTrap Technologies

LigaTrap Technologies develops affinity chromatography resins and purification buffers, ELISA kits and reagents, and recombinant proteins. LigaTrap also provides services including custom protein purification and analytical assay development.

Raleigh
Lindy Biosciences Inc.

Lindy Biosciences develops protein therapeutic formulations for non-standard formulations such as suspension formulations (for high-concentration delivery of antibodies), encapsulation (for sustained/controlled release) or dry powder pulmonary delivery.

Research Triangle Park
Liquidia Technologies Inc.

Liquidia Technologies develops and commercializes human therapeutics for the treatment of pulmonary arterial hypertension and post-operative pain using its proprietary particle engineering technology.

Morrisville
MARBIONC Development Group LLC

MARBIONC Development Group is a nonprofit organization that develops and markets new products and technologies derived from marine and aquatic organisms.

Wilmington
Medicago USA Inc.

Medicago develops vaccines based on proprietary manufacturing technologies and virus-like particles. The vaccines are manufactured using a transient protein expression system in Nicotiana benthamiana, a close relative of tobacco.

Durham
MEDTOX Diagnostics Inc.

MEDTOX Diagnostics manufactures and distributes instant drugs of abuse testing devices for use by the government, hospital and medical centers and workplace markets.

Burlington
MoHu

MoHu uses fungi and yeast to convert cellulose and wood components to novel protein-rich meat and soluble carboyhdrate replacements.

Research Triangle Park
Mycosynthetix Inc.

Mycosynthetix manages a large collection of fungal isolates and discovers novel fungal metabolites for human and animal health and compounds for agricultural applications.

Hillsborough
NanoCor Therapeutics Inc.

NanoCor Therapeutics develops an intracellular genetic protein therapy for the treatment of chronic heart failure.

Research Triangle Park
NanoMedica LLC

NanoMedica provides ultrasensitive detection reagents and nanotechnology-based drug discovery services and tools to biopharmaceutical companies as well as DNA and RNA sequencing services.

Winston-Salem
NCSU Technology Incubator

The NCSU Technology Incubator at Centennial Campus offers a program and facilities specifically designed for tech start-ups with high-impact potential.

Raleigh
Nitta Gelatin NA Inc.

Nitta Gelatin manufactures food, pharmaceutical and technical gelatin, and is the maker of beMatrix Low Endotoxin Gelatin. beMatrix is used in the fields of regenerative medicine, medical devices and scientific research.

Morrisville
Nitta Gelatin NA Inc. (Fayetteville)

Nitta Gelatin's Fayetteville plant produces 3,000 tons of pharmaceutical and food-grade gelatins per year. Nitta Gelatin provides many different grades of gelatin for a variety of uses in the pharmaceutical industry.

Fayetteville
Noah's Inc.

Noah’s Inc. develops algal growth systems and cultivates algal biomass for the manufacture of protein, astaxanthin and other derivatives for use as nutraceutical ingredients in food and beverage industries, and for commercial fish/animal feed industries.

Charlotte
Novex Innovations LLC

Novex Innovations is a contract development and manufacturing organization (CDMO) supporting small and startup life science companies in the development of their products, from concept through manufacturing and commercialization.

Winston-Salem
Novozymes BioAg

Novozymes BioAg develops microbial-based biofertility, biocontrol and bioyield enhancer products for agriculture. The Morrisville site focuses on fermentation and production technology.

Morrisville
Novozymes North America Inc.

Novozymes researches, develops and manufactures enzymes, microorganisms and biopharmaceutical ingredients used in industries including agriculture, baking, biofuels, brewing, detergents, food, feed and textiles. The Franklinton site manufactures enzymes.

Franklinton
Parion Sciences Inc.

Parion Sciences develops therapies to treat defects of the innate mucosal defense system in respiratory and ophthalmology diseases.

Durham
Phytobiotics North America LLC

Phytobiotics produces and distributes botanical and phytogenic supplements and flavors for plant and animal nutrition. Additionally, Phytobiotics provides consultative services focused on intestinal health and increased nutrient bioavailability.

Cary
Plakous Therapeutics LLC

Plakous Therapeutics is developing biotherapeutics from post-delivery placenta to promote regenerative healing for diseases including osteoarthritis, necrotizing enterocolitis, wound healing and tissue engraftment.

Winston-Salem
Plant Health Care Inc.

Plant Health Care develops and provides novel biological products and technologies to promote plant health and increase crop yields.

Raleigh
Precision BioSciences Inc.

Precision BioSciences utilizes a proprietary genome editing method called ARCUS to treat cancers and genetic diseases, and enable the development of safer, more productive food sources.

Durham
QNS Group LLC

QNS Group offers consulting in translational medicine, analytical biotechnology, biopharmaceuticals, medical devices and diagnostics. Services include virtual discovery, product design and development, including regulatory advice.

Bahama
Rescindo Therapeutics Inc.

Rescindo Therapeutics discovers novel therapeutic targets and drugs for human genetic disorders based on humanized zebrafish in vivo modeling.

Durham
RiboWiz Scientific Inc.

RiboWiz Scientific uses a proprietary platform to offer customized software services and cloud-based subscription licensing to accurately predict and maximize protein production for life science companies.

Raleigh
RTI International

RTI, an independent, nonprofit institute, offers scientific and technical expertise in social and laboratory sciences, engineering and international development to government and commercial clients worldwide.

Research Triangle Park

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