NCBiotech Company Directory is a comprehensive listing of North Carolina's life science industry New search

Company Title Company Description City

3i Nano develops point-of-care devices for disease diagnostics and protein detection.

410 Medical Inc.

410 Medical is developing technology for rapid infusion of fluids and blood products for hospital, transport and military healthcare providers, enabling clinicians to quickly and effectively resuscitate critically ill patients.

Adhezion Biomedical LLC

Adhezion Biomedical develops and produces cyanoacrylate-based medical adhesive, wound care and microbial barrier products for connective tissue (human skin). The company's manufacturing and research facility is located in Hudson, N.C.

Advanced Chemotherapy Technologies Inc.

Advanced Chemotherapy Technologies, a UNC startup, has developed a novel device for infusing chemotherapies directly into poorly-vascularized pancreatic tumors.

Aegis Surgical Ltd.

AEGIS is developing a less invasive access system that facilitates percutaneous transaortic transcatheter aortic valve replacement (pTAo-TAVR).

Aerami Therapeutics

Aerami Therapeutics develops soft mist inhaled formulations of biologics and inhalation devices to treat severe and chronic diseases. Its first product is for the treatment of diabetes.

Akros Medical Inc.

Akros Medical develops orthopedic medical devices.

Alievio Inc.

Alievio is developing an ocular implant to treat late stage glaucoma.

Research Triangle Park
Allwell Medical Corp.

Allwell Medical manufactures interventional cardiology accessories including inflation devices, coronary control injection sets, balloons and catheters.

Altadonics Corp.

Altadonics makes dentures using a denture molding technique that captures, saves and stores a mold of the denture, allowing for rapid denture replacement.

Andersen Products Inc.

Andersen Products sells and services the Anprolene and EOGas lines of 100% ethylene oxide gas sterilizers. They also provide contract packaging and sterilization services for device manufacturers.

Haw River

AnelleO is developing a 3D-printed intravaginal ring that can be used for treating infertility and a wide range of other women's health conditions.

Chapel Hill
Applied Catheter Technologies Inc.

Applied Catheter Technologies develops drug-coated medical devices that inhibit scar formation. The company's first products under development are catheters for male urethral stricture and devices that inhibit abdominal adhesions.

ATEX Technologies Inc.

ATEX manufactures custom engineered implantable textile components for medical devices. Components are manufactured using weaving, knitting, braiding and non-woven technologies. Raw materials include polyester, bio-absorbable polymers and metals.

Atlantic Medical Inc.

Atlantic Medical develops nutraceutical products and devices to address ocular diseases.

Wrightsville Beach
Avioq Inc.

Avioq is an in vitro diagnostic medical device manufacturer, contract development and contract manufacturing organization operating an FDA licensed manufacturing facility and research and development laboratories.

Research Triangle Park
Baxter Healthcare Corp.

Baxter's facility in Marion produces intravenous and peritoneal dialysis solutions, as well as empty containers and component parts for other Baxter facilities.

BD Diagnostics (Durham)

BD Diagnostics develops and commercializes molecular diagnostic products for various cancers, including cervical, breast, ovarian and prostate.

BD Diagnostics (Mebane)

BD Diagnostics develops and commercializes molecular diagnostic products for women's health and various cancers.

BD Technologies and Innovation

BD Technologies and Innovation develops technologies for parenteral drug delivery, advanced diagnostics, smart medical devices and genomic research and supports external innovation. The RTP site is BD's corporate technology R&D and innovation center.

Research Triangle Park
BioMedInnovations LLC

BioMedInnovations (BMI) makes precision air and fluid flow devices, including products for lung ventilators and ex-vivo organ and tissue perfusion.

bioMérieux Inc.

bioMérieux develops in vitro products to diagnose infectious diseases, cancer and cardiovascular disease and to detect microorganisms in agri-foods, pharmaceuticals and cosmetics.

Bioventus LLC

Bioventus develops and markets orthobiologic solutions for musculoskeletal healing and regeneration. The Innovations For Active Healing from Bioventus include offerings for osteoarthritis, surgical and non-surgical bone healing.

Catalyst Medicine LLC

Catalyst Medicine designs, develops and commercializes Class 1 and Class 2 medical devices in the areas of neurology, orthopedics, cardiology and plastic surgery.

Cathtek Inc.

Cathtek develops and manufactures catheters and related accessories.

Chesson Laboratory Associates Inc.

Chesson Labs develops prescription and over-the-counter polymer-based medical products for wound care and skin and nail care products.


Circassia develops and markets products to aid in the diagnosis and control of asthma, COPD and allergy.

CivaTech Oncology Inc.

CivaTech Oncology has developed targeted implantable radiation devices to treat many cancer types. Products provide a targeted, customized radiation dose during a surgical resection procedure or in outpatient therapies to treat cancers.

Columbia Life Systems Inc.

Columbia Life Systems is developing a computer-controlled oxygen blender for therapeutic research.

Chapel Hill
Concentrx Pharmaceuticals Inc.

Concentrx develops inhaled prescription products for asthma and COPD, including a unit dose disposable dry powder inhaler.

Contego Medical LLC

Contego Medical develops embolic protection devices for cardiovascular and peripheral vascular procedures, designed to simplify catheter-based procedures.

ConvaTec Inc.

ConvaTec develops and manufactures therapies for the management of chronic conditions, with a focus on advanced wound care, ostomy care, continence and critical care and infusion devices. The Triad site is the company's Global Quality Headquarters.

Cook Medical

Cook Medical develops and manufactures devices used in gastrointestinal endoscopy to diagnose and treat esophageal, gastric, pancreatic, biliary and colonic disorders.

CorneaGen Inc.

CorneaGen provides corneal endothelial cells for transplantation, as well as related supplies and devices. It is an FDA-registered human tissue establishment.

Curasan Inc.

Curasan develops, manufactures and markets biomaterials for bone and tissue regeneration. This site is a sales and marketing location for North America.

Wake Forest
Cytex Therapeutics Inc.

Cytex Therapeutics develops bio-artificial devices to treat osteoarthritis and other musculoskeletal diseases.

DaVINCI Biomedical Research Products Inc.

DaVINCI Biomedical Research is an AAALAC-accredited contract lab that performs GLP and non-GLP preclinical animal studies. DaVINCI specializes in regenerative medicine, cardiovascular, orthopedic and medical device applications.

Deep Blue Medical Advances Inc.

Deep Blue Medical Advances develops a surgical mesh for hernia repair and other medical device technologies from Duke University.

Diabetic Health Inc.

Diabetic Health develops coatings to improve the longevity and performance of continuous glucose monitoring sensors (CGM) and insulin infusion sets used in diabetes management.

Research Triangle Park
Diamond Orthopedic LLC

Diamond Orthopedic has developed and markets proprietary bone screw technology for orthopedic fixation.

ENCO Pharmaceutical Development Inc.

ENCO Pharmaceutical Development Inc. (EPDI) provides analytical services, comprehensive stability storage and related testing, as well as a product and formulation development services.

Entegrion Inc.

Entegrion develops biologic and medical device technologies, such as a novel point of care in vitro diagnostic viscoelastic blood coagulation monitoring system for use in human and veterinary medicine.

FHI 360

FHI 360 is a nonprofit human development organization working to improve the health and well-being of people in the U.S. and around the world. The laboratory in Durham offers medical device and pharmaceutical testing services.

Fresenius Kabi USA LLC

Fresenius Kabi manufactures medical devices and sterile injection- and infusion-based drug-delivery products.

Harmony Development Group

Harmony Development Group is developing a passive intra-ventricular cardiac assist device that can slow down, stop and even reverse the cascade of heart failure dysfunction.

HepatoSys Inc.

HepatoSys develops technologies for functional restoration and storage of organs, tissues and cells for use in research and therapeutic applications.

InnAVasc Medical Inc.

InnAVasc Medical designs and develops products for vascular access. The company's first technology is an arteriovenous graft (AVG) modification that facilitates graft access and safety in hemodialysis.

KlearOptix Inc.

KlearOptix develops materials for ophthalmic application such RGP, soft lense and IOL.

Knightpoint Group LLC

Knightpoint Group offers contract development and manufacturing services, specializing in parenteral and respiratory drug delivery products. Knightpoint Group is also developing a platform capsule inhaler technology for large doses.

Leica Microsystems Inc.

Leica Microsystems manufactures microscopes and scientific instruments for the analysis of microstructures and nanostructures. Its Morrisville site develops optical coherence tomography imaging systems for ophthalmology preclinical research and surgery.

Lucerno Dynamics LLC

Lucerno Dynamics is commercializing a noninvasive device for quality assurance and control in nuclear medicine imaging. Future applications of the technology include rheumatoid arthritis, immunotherapy, nuclear medicine and chemotherapy assessment.

Lumedica Vision Inc.

Lumedica Vision develops Optical Coherence Tomography (OCT) systems for research and clinical applications.

MED-EL Corporation USA

Med-El researches and develops cochlear implant technology. The Durham location manufactures cochlear implants and is also the North American headquarters.

Medical Facets NC LLC

Medical Facets manufactures prosthetics and bone fixation screws and pins.

Medical Murray

Medical Murray is a contract developer and manufacturer of medical devices with a focus on minimally-invasive systems, permanent implants, injection molding and specialty materials (e.g. bioabsorbables, ePTFE and nitinol).

MEDTOX Diagnostics Inc.

MEDTOX Diagnostics manufactures and distributes instant drugs of abuse testing devices for use by the government, hospital and medical centers and workplace markets.

Micell Technologies Inc.

Micell Technologies develops combination-product therapies for interventional cardiology. Micell markets MiStent, a drug-eluting stent, in Europe and certain other regions.

MicroElastic Ultrasound Systems Inc.

MicroElastic Ultrasound Systems is developing a portable platform for tissue elasticity measurement at the point of care.

Migraine Solutions LLC

Migraine Solutions is developing Relaspen, an intra-nasal medical device which applies lidocaine directly to the SPG (Sphenopataline Ganglion) nerve, reducing migraines.

Minu LLC

Minu researches and develops ophthalmology products.

Chapel Hill
Mucommune LLC

Mucommune is developing a platform using monoclonal antibodies and mucus to reinforce the mucus barrier for female reproductive health.

NeuroTronik Inc.

NeuroTronik develops medical technology for the treatment of acute heart failure syndrome.

Nocturnal Product Development LLC

Nocturnal Product Development provides contract design and development services for Class II and Class III medical devices. The company is also developing an ablation catheter that enables real-time visualization of ablated cardiac tissue.

Novex Innovations LLC

Novex Innovations is a contract development and manufacturing organization (CDMO) supporting medium, small and startup life science companies in the development of their products, from concept through manufacturing and commercialization.


Textile-Based Delivery develops and manufactures fabrics that integrate controlled release matrices, offering topical and transdermal dosing of active ingredients.


NuPulseCV is developing an implantable cardiovascular left ventricular assist device to treat people suffering from congestive heart failure.

Oriel Therapeutics Inc., a Sandoz company (Durham)

Oriel operates as Sandoz' product development center, which develops respiratory products as generic alternatives to patented drugs for asthma and COPD. It also develops and commercializes pre-metered unit and multi-dose dry powder delivery systems.

Parion Sciences Inc.

Parion Sciences develops therapies to treat defects of the innate mucosal defense system in respiratory and ophthalmology diseases.

Pearl Therapeutics Inc.

Pearl Therapeutics, a subsidiary of AstraZeneca, develops combination therapies and formulations of inhaled drugs for chronic respiratory diseases such as asthma and COPD.

Performance Orthopaedics of the Carolinas Inc.

Performance Orthopaedics of the Carolinas is a distributorship for DePuy Orthopaedics. Performance Orthopaedics sells DePuy's orthopedic devices and supplies.

Pfizer Inc. (Rocky Mount)

Pfizer's Rocky Mount facility manufactures injectable hospital products. The facility also provides contract manufacturing services such as aseptic filling, lyophilization and terminal sterilization.

Rocky Mount
Phoenix Cardiac Devices Inc.

Phoenix Cardiac Devices is designing and developing a cardiac device to treat functional mitral valve regurgitation.

Piedmont BioMed Inc.

Piedmont BioMed designs implantable biosensors for various clinical, medical and surgical applications.

Polarean Inc.

Polarean designs and manufactures equipment for production of hyperpolarized xenon or helium gas for use in MRI. Investigational uses include identifying early diagnoses of respiratory diseases as well as monitoring progression and therapeutic response.

Polyzen Inc.

Polyzen is a contract manufacturer that designs, develops, and manufactures polymer-based medical devices. Polyzen has polymer processing capabilities for prototyping and volume production.

RAIN Scientific Inc.

Rain Scientific is developing technologies to combat pathogens such as COVID-19 and drug resistant bacteria.


Raumedic manufactures polymer components used in the medical and pharmaceutical industry, including catheters, drug delivery systems, opthalmology sets and surgical devices parts.

Mills River
Realtromins Inc.

Realtromins has created a family of medical devices for real time risk assessment of critically ill and hospitalized infants and children, providing clinical decision support for healthcare providers.

Chapel Hill
Revian Inc.

Revian has developed and markets a light therapy hair growth system.

RFPi Inc.

RFPi is developing, manufacturing and marketing platform technology for non-invasive surgical imaging that enables the providers to see real-time images of blood flow distribution and tissue perfusion without patient contact or injection of dye.

RTI Surgical Inc.

RTI Surgical develops and provides surgical implants, including biologic, metal and synthetic implants.

Saebo Inc.

Saebo provides rehabilitation products for the neurological patient.

SEAL Innovation Inc.

SEAL Innovation Inc has developed a swim monitoring and drowning detection system called the SEAL SwimSafe.

SonaCare Medical

SonaCare Medical develops minimally-invasive ultrasound technologies that ablate targeted soft tissue for the treatment of cancer.

SonoVascular Inc.

SonoVascular is developing a thrombolysis device for the treatment of blood clots related to deep vein thrombosis, pulmonary embolism and peripheral arterial occlusions.

Chapel Hill
SonoVol Inc.

SonoVol is developing preclinical imaging technology that can be applied to the animal models that researchers use to evaluate the efficacy and toxicity of new drugs before they enter clinical trials.

Spin-Darc LLC

Spin-Darc is developing a rapid digital microbiology testing device usable at point-of-care or in low-resource settings. Applications include infectious disease diagnostics, food testing and water testing.

Stallergenes Greer

Stallergenes Greer develops and distributes animal and human allergy immunotherapy products and services.

Structure Medical Inc.

Structure Medical is a contract manufacturer of orthopedic medical devices, including implantable orthopedic fracture fixation and spinal instrumentation products.


Stryker provides medical technology products with a focus in orthopaedics, neurotechnology and surgical devices. The Durham site developed and manufactures a surgical sealant device for use during cranial procedures.

SunTech Medical Inc.

SunTech Medical manufactures non-invasive blood pressure monitoring products and technology.

Surgilūm LLC

Surgilūm designs, manufactures and markets medical instruments for use in cataract and refractive surgery.

Teleflex Medical

Teleflex Medical designs, manufactures and distributes medical devices, surgical instruments and disposable medical products.

TheraBionic Inc.

TheraBionic is developing treatment approaches for cancer based on the use of tumor-specific modulation frequencies, with an initial focus in hepatocellular carcinoma.


TIRF Labs develops, manufactures and markets a broad range of products based on total internal reflection fluorescence (TIRF), including add-on TIRF accessories for microscopy and spectroscopy, TIRF biosensors and fluorescence illuminators.

TransEnterix Inc.

TransEnterix develops and sells instruments and robotics for laparoscopic minimally invasive surgery.

TriboFilm Research Inc.

TriboFilm Research develops low-friction, thin-film coating and lubrication platforms for medical devices and for the aerospace and marine industries.

Tryton Medical Inc.

Tryton Medical develops and sells stent systems for the treatment of coronary artery bifurcation lesions.

UCB Biosciences Inc.

UCB Biosciences develops therapeutics for the treatment of severe, life-threatening neurological and inflammatory diseases, including epilepsy, Parkinson's disease, rheumatoid arthritis, Crohn's disease, psoriatic arthritis, lupus and osteoporosis.

URO-1 Inc.

URO-1 develops solutions for office procedures for urologic health. Its FDA-cleared Repris Bladder Injection System improves outcomes in women with overactive bladder (OAB).