Production and Manufacturing

AccuGenomics manufactures custom gene expression tests to diagnose and monitor cancer treatment. Its technologies include Standard Nucleic Acid Quantification for RNA and DNA Sequencing for any NGS platform analysis.

Ajinomoto North America manufactures pharmaceutical-grade amino acids and custom-blended amino acid mixtures.

Allergy Partners' Extract Laboratory produces extracts that are used to treat allergic disease, asthma and immunology.

American Distillation manufactures industrial-grade ethyl alcohol and offers contract manufacturing services such as distillation, dehydration, reaction, carbon treating and blending.

Andersen Products sells and services the Anprolene and EOGas lines of 100% ethylene oxide gas sterilizers. They also provide contract packaging and sterilization services for device manufacturers.

Arspichem offers chemical product services to pharma, biotech industries, universities and research organizations to support drug discovery. Products and services include organic molecules, custom synthesis and pharmaceutical screening libraries.

ATEX manufactures custom engineered implantable textile components for medical devices. Components are manufactured using weaving, knitting, braiding and non-woven technologies. Raw materials include polyester, bio-absorbable polymers and metals.

Avila is developing rapid hair removal pad technology for use prior to the placement of defibrillator pads on victims of sudden cardiac arrest.

Avoca develops and manufactures botanical extraction products, provides extraction services and contracts with farmers to grow clary sage.

Baebies develops and commercializes products and services based on digital microfluidics and other technology that ensure early disease detection and comprehensive diagnosis for children.

BD Diagnostics develops and commercializes molecular diagnostic products for various cancers, including cervical, breast, ovarian and prostate.

BestCo manufactures over-the-counter drugs and dietary supplements and offers contract product manufacturing and packaging.

Biogen discovers, develops and manufactures therapies for serious neurological diseases. Its Drug Substance Campus in RTP is home to biologics production and a patient services contact center.

BioGreen Synergy manufactures, grows and provides algae-based products for use in alternative renewable energies, USDA, non-USDA and chemical markets.

BioTek Ag produces plant growth regulators, nutritional products, surfactants and other specialty products to enhance soil biology and crop input effectiveness.

bluebird bio develops gene therapies and cancer immunotherapies for the treatment of genetic diseases and cancer. At its Durham site, bluebird produces lentiviral vectors for the company's gene and cell therapies.

Cambrex High Point develops and manufactures small-molecule APIs and intermediates for Phase I through III clinical trials. It offers custom organic synthesis, process development, analytical development and cGMP manufacturing services.

Cellectis develops blood and bone marrow cancer cell therapies. The Raleigh location is its North American manufacturing plant.

CharGrow has developed and manufactures and distributes organic biochar-based probiotics for agriculture and horticulture.

Charter Medical designs and supplies single-use solutions for cell growth, frozen storage and biological fluid handling for the bioprocessing, cell therapy and medical device industries. CML is FDA-registered and ISO 13485-certified.

Chemring Sensors and Electronic Systems develops and manufactures chemical and biological agent detection systems, as well as explosive detection systems.

CMP develops, manufactures and commercializes specialty pharmaceuticals, focused on niche liquid and topical products that solve unmet patient needs.

Cook Medical develops and manufactures devices used in gastrointestinal endoscopy to diagnose and treat esophageal, gastric, pancreatic, biliary and colonic disorders.

Creative PEGWorks manufactures and supplies advanced functional polymer products for research. Main product lines include PEG, polysaccharides, biodegradable polyester, copolymers and PEGylation service.

Daily Manufacturing manufactures vitamins, minerals and herbals. The company also manufactures products for other supplement companies with their own brand names.

Ecoblend develops and manufactures organic weed and pest control products.

Exela Pharma Sciences develops, manufactures and markets sterile injectable pharmaceuticals and provides contract manufacturing services. The Lenoir site is a cGMP-compliant sterile manufacturing facility.

Fleming Laboratories manufactures animal pharmaceuticals.

North American Bio-Energies (NABE), doing business as Foothills Bio-Energies LLC, produces biodiesel from virgin agri-based feedstock.

Fujifilm Diosynth Biotechnologies provides biologics contract development and manufacturing. Services include cell line development, process and analytical development, clinical and commercial manufacturing and bioprocess research and development.

Gaia Herbs grows and produces certified organic herbal products, including liquid extracts, functional powders and herbal teas. All growing, manufacturing, processing, researching, packaging and distribution takes place in its North Carolina facilities.

Glenmark Pharmaceuticals discovers small-molecule drugs and biologics in the areas of oncology, respiratory disease and dermatology, and manufactures and distributes APIs and generics. The Monroe site manufactures oral solids, injectables and topicals.

Goldsboro Laboratories develops and manufactures vaccines for the swine, poultry and cattle divisions of Goldsboro Milling Company.

GlaxoSmithKline manufactures solid-dose products, including tablets and capsules, at its Zebulon facility. The plant also does granulation, drying and packaging, and contract manufacturing of antibiotics for other companies.

Happy Jack manufactures insecticides and pharmaceutical preparations to treat dogs.

Hemo Bioscience is an FDA-registered, ISO 13485-accredited manufacturer of blood-typing reagents and diagnostics for the blood-banking industry.

HTX Technologies develops tissue imaging and molecular imaging technologies, with a primary focus on sample preparation and mass spectrometry imaging.

ImmunoReagents manufactures primary and secondary polyclonal antibodies used in research and in vitro diagnostics for the pharmaceutical and veterinary markets.

Integrated DNA Technologies develops and manufactures nucleic acid products for the life sciences industry. IDT manufactures products used in diagnostic tests for many forms of cancer and most inherited and infectious diseases.

Juno Metabolomics is developing next-generation metabolomics for precision medicine.

KBI Biopharma offers contract development and biopharmaceutical manufacturing services. This site is KBI's process development facility.

Kriya Therapeutics develops AAV-based gene therapies for the treatment of type 1 and type 2 diabetes, severe obesity, and other indications.

Lonza provides bioscience products and services ranging from cell culture and discovery technologies for research to quality control tests and software that ensures product quality. Its RTP site produces hepatocytes for use in drug research.

Mayne Pharma manufactures branded and generic oral solid dose pharmaceuticals. The Greenville site is Mayne Pharma’s U.S. development and manufacturing facility.

MEDTOX Diagnostics manufactures and distributes instant drugs of abuse testing devices for use by the government, hospital and medical centers and workplace markets.

Merck's Wilson facility produces patented prescription products and performs granulation and tableting operations.

MOLTOX manufactures products used in mutagenicity testing and human risk assessment, as well as prepared bacteriological media including nutrient, selective and enrichment media used in industrial, environmental and molecular microbiology.

Nitta Gelatin manufactures food, pharmaceutical and technical gelatin and is the maker of beMatrix Low Endotoxin Gelatin. beMatrix is used in the fields of regenerative medicine, medical devices and scientific research.

Noah’s Inc. develops algal growth systems and cultivates algal biomass for the manufacture of protein, astaxanthin and other derivatives for use as nutraceutical ingredients in food and beverage industries, and for commercial fish/animal feed industries.