Production and Manufacturing

908 Devices develops and makes chemical analysis products such as handheld chemical detection tools, compact analyzers and separation devices.

Adámas Nanotechnologies develops and produces fluorescent nanodiamond particles for life science, medical and industrial applications, including life science research, drug delivery, bioimaging, anti-counterfeiting, oil additives and cosmetics.

Alcami provides contract drug and biologics development and manufacturing services, including formulation development, analytical chemistry, API, solid dose and parenteral drug manufacturing for both clinical and commercial markets.

Allergy Partners' Extract Laboratory produces extracts that are used to treat allergic disease, asthma and immunology.

American Distillation manufactures industrial-grade ethyl alcohol and offers contract manufacturing services such as distillation, dehydration, reaction, carbon treating and blending.

Andersen Products sells and services the Anprolene and EOGas lines of 100% ethylene oxide gas sterilizers. They also provide contract packaging and sterilization services for device manufacturers.

Arspichem offers chemical product services to pharma, biotech industries, universities and research organizations to support drug discovery. Products and services include organic molecules, custom synthesis and pharmaceutical screening libraries.

Astral genetics offers a range of fee-for-service products relating to the generation and characterization of mouse and human induced pluripotent Stem Cells (iPS).

Avient Biosciences produces cannabinoid-derived products, CBD oil, CBD isolate, water soluble CBD, and other isolated cannabinoid compounds. Avient is in process to be a cGMP compliant extraction facility.

Avoca develops and manufactures botanical extraction products, provides extraction services and contracts with farmers to grow clary sage.

Baebies develops and commercializes products and services based on digital microfluidics and other technology that ensure early disease detection and comprehensive diagnosis for children.

BD Diagnostics develops and commercializes molecular diagnostic products for various cancers, including cervical, breast, ovarian and prostate.

Beam Therapeutics will manufacture precision genetic medicines through the use of base editing technology at its RTP site.

Bio-Pro Research manufactures and distributes bio-enzymatic products for stain and odor removal.

Biogen discovers, develops and manufactures therapies for serious neurological diseases. This site houses oral solid dose and anti-sense oligonucleotide production, packaging and fill/finish operations, as well as a Global Business Services center.

BioTek Ag produces plant growth regulators, nutritional products, surfactants and other specialty products to enhance soil biology and crop input effectiveness.

bluebird bio develops gene therapies and cancer immunotherapies for the treatment of genetic diseases and cancer. At its Durham site, bluebird produces lentiviral vectors for the company's gene and cell therapies.

Cambrex High Point develops and manufactures small-molecule APIs and intermediates for Phase I through III clinical trials. It offers custom organic synthesis, process development, analytical development and cGMP manufacturing services.

Cellectis develops blood and bone marrow cancer cell therapies. The Raleigh location is its North American manufacturing plant.

Centre Ingredient Technology develops natural flavors and fragrance ingredients for the food, beverage and cosmetics industry using fermentation. CIT also provides contract development, toll manufacturing and biotransformation services.

Charles River Laboratories provides drug discovery and development process services.

ChemQ Bioscience develops and markets novel liquid products, such as bio-preservation media, tissue perfusion solutions and liquid-based cytology processing kits. ChemQ also offers contract research services and custom formulation.

Chirazyme produces chloroperoxidase for use in a variety of assays and in stereospecific epoxidation reactions.

CoImmune develops and manufactures cell-based therapeutics to treat unmet medical needs including cancer, autoimmune and inflammatory diseases. CoImmune also provides cGMP consulting and manufacturing of third-party clinical stage cell-based products.

Corning Life Sciences manufactures pipettes, conical and round-bottomed tubes, cell inserts, tissue-culture plates and ADME/Toxicology products.

Cygnus Technologies, part of Maravai LifeSciences, develops products and services for the biopharma industry, including host cell protein (HCP) and other process-related impurity detection and analytics as well as viral clearance solutions.

Diamond Orthopedic has developed and markets proprietary bone screw technology for orthopedic fixation.

Exela Pharma Sciences develops, manufactures and markets sterile injectable pharmaceuticals and provides contract manufacturing services. The Lenoir site is a cGMP-compliant sterile manufacturing facility.

Fleming Laboratories manufactures animal pharmaceuticals.

North American Bio-Energies (NABE), doing business as Foothills Bio-Energies LLC, produces biodiesel from virgin agri-based feedstock.

Fujifilm Diosynth Biotechnologies provides biologics contract development and manufacturing. Services include cell line development, process and analytical development, clinical and commercial manufacturing and bioprocess research and development.

Gaia Herbs grows and produces certified organic herbal products, including liquid extracts, functional powders and herbal teas. All growing, manufacturing, processing, researching, packaging and distribution takes place in its North Carolina facilities.

Glycan Therapeutics offers synthetic carbohydrates of various lengths to aid researchers investigating multiple therapeutic areas. Glycan also offers custom synthesis and array analysis of heparan and chondroitin sulfate oligosaccharides derivatives.

GlaxoSmithKline manufactures solid-dose products, including tablets and capsules, at its Zebulon facility. The plant also does granulation, drying and packaging, and contract manufacturing of antibiotics for other companies.

Happy Jack manufactures insecticides and pharmaceutical preparations to treat dogs.

Hemo Bioscience is an FDA-registered, ISO 13485-accredited manufacturer of blood-typing reagents and diagnostics for the blood-banking industry.

HTX Technologies develops tissue imaging and molecular imaging technologies, with a primary focus on sample preparation and mass spectrometry imaging.

ImmunoReagents manufactures primary and secondary polyclonal antibodies used in research and in vitro diagnostics for the pharmaceutical and veterinary markets.

Integrated DNA Technologies develops and manufactures nucleic acid products for the life sciences industry. IDT manufactures products used in diagnostic tests for many forms of cancer and most inherited and infectious diseases.

Juno Metabolomics is developing next-generation metabolomics for precision medicine.

KBI Biopharma offers contract development and biopharmaceutical manufacturing services. This site is KBI's process development facility.

KriGen Pharmaceuticals develops pharmaceutical products, and provides finished product formulation solutions and sterile active pharmaceutical ingredients to generic and branded pharmaceutical companies.

LigaTrap Technologies provides proprietary affinity chromatography resins and supporting products. LigaTrap also provides custom services for process development, small batch cell culture, scale up purification and assays.

Lonza provides bioscience products and services ranging from cell culture and discovery technologies for research to quality control tests and software that ensures product quality. Its RTP site produces hepatocytes for use in drug research.

Mallinckrodt manufactures acetaminophen, the active ingredient in Tylenol, at its pharmaceutical facility in Raleigh.

Medical Murray is a contract developer and manufacturer of medical devices with a focus on minimally-invasive systems, permanent implants, injection molding and specialty materials (e.g. bioabsorbables, ePTFE and nitinol).

Merck manufactures vaccine products at its Durham facility.

Mirimichi Green manufactures nontoxic landscape products, including turf and tree care products, seed and soil enhancers and protectants and weed and grass control herbicides.

Natland International provides contract research synthesis of pharmaceuticals and custom organic chemicals.