Research and Development

NCBiotech Company Directory is a comprehensive listing of North Carolina's life science industry New search

Company Title Company Description City
StrideBio Inc.

StrideBio develops engineered viral vectors for gene therapy for the treatment of rare diseases. StrideBio's technology engine utilizes structure-inspired design to engineer AAV vectors which can escape pre-existing neutralizing antibodies (NAbs).

Research Triangle Park
21MedTech

21MedTech develops and offers advanced, proprietary, bioresorbable resins for controlled release drug delivery, regenerative devices and 3D manufacturing.

Holly Springs
3i-Nano

3i Nano develops point-of-care devices for disease diagnostics and protein detection.

Greensboro
410 Medical Inc.

410 Medical is developing technology for rapid infusion of fluids for hospital, transport and military healthcare providers, enabling clinicians to quickly and effectively resuscitate critically ill patients.

Durham
Achelios Therapeutics Inc.

Achelios Therapeutics develops novel topical therapeutics for the treatment of inflammatory pain, including migraine and temporomandibular joint disorder pain.

Durham
Adhezion Biomedical LLC

Adhezion Biomedical develops and produces cyanoacrylate-based medical adhesive, wound care and microbial barrier products for connective tissue (human skin). The company's manufacturing and research facility is located in Hudson, N.C.

Hudson
Adrenas Therapeutics Inc.

Adrenas Therapeutics is developing a gene therapy for the treatment of a monogenic disease that presents in childhood.

Raleigh
Advanced Animal Diagnostics Inc.

Advanced Animal Diagnostics (AAD) develops and commercializes diagnostics to detect and manage disease states, reproductive, nutritional and overall health status of production animals.

Morrisville
Advanced Chemotherapy Technologies Inc.

Advanced Chemotherapy Technologies, a UNC startup, has developed a novel device for infusing chemotherapies directly into poorly-vascularized pancreatic tumors.

Raleigh
Aegis Surgical Ltd.

AEGIS is developing a less invasive access system that facilitates percutaneous transaortic transcatheter aortic valve replacement (pTAo-TAVR).

Durham
AegisCN LLC

AegisCN develops technologies and treatments targeting neurological diseases and inflammation.

Durham
Aerami Therapeutics

Aerami Therapeutics develops soft mist inhaled formulations of biologics and inhalation devices to treat severe and chronic diseases. Its first product is for the treatment of diabetes.

Durham
Aerie Pharmaceuticals Inc.

Aerie Pharmaceuticals discovers, develops and commercializes first-in-class therapies for the treatment of patients with glaucoma.

Durham
Aestas Pharma Inc.

Asetas Pharma develops novel diagnostic imaging and disease-modifying therapeutic agents to enable the early treatment and reversal of Alzheimer’s and Parkinson’s disease when clinical signs are not yet pronounced.

Lewisville
Affinergy LLC

Affinergy develops peptide-based technologies, including diagnostic products, research tools and therapeutic drug monitoring products for use by clinicians and researchers.

Morrisville
AgBiome Inc.

AgBiome uses its proprietary Genesis platform to collect, isolate and analyze microbes for use in the discovery and development of biologicals and traits for protecting crops and is researching probiotic products to address swine gut health challenges.

Research Triangle Park
Agile Sciences Inc.

Agile Sciences is developing a technology for the treatment of antibiotic-resistant, life-threatening infections.

Raleigh
AI Tracking Solutions LLC

AI Tracking Solutions develops a single-particle tracking software that tracks entities including nanoparticles, viruses, bacteria and cells within fluids and biological samples and generates individual traces and statistical analysis of the traces.

Carrboro
AimMax Therapeutics Inc.

AimMax Therapeutics researches and develops biopharmaceuticals for the treatment of infection, inflammation and pain through in-licensing or co-development with strategic partners.

Durham
Akros Medical Inc.

Akros Medical develops orthopedic medical devices.

Durham
Alderon BioSciences Inc.

Alderon Biosciences develops point-of-care diagnostics.

Beaufort
ALG Therapeutics LLC

ALG Therapeutics develops pharmaceutical products for pain disorders.

Chapel Hill
Algaen Corp.

Algaen uses microalgae to develop, produce and market products and technologies for the nutraceutical, pharmaceutical and bio-energy industries.

Winston-Salem
Alievio Inc.

Alievio is developing an ocular implant to treat late stage glaucoma.

Research Triangle Park
ALP Life Sciences Inc.

ALP Life Sciences has formulated and markets a High-3 fish oil supplement to increase omega-3 absorption and bioavailability for the treatment of fatty liver disease and inflammatory diseases.

Black Mountain
AlphaVax Inc.

AlphaVax develops vaccine technology with applications in infectious disease, cancer and biodefense threats.

Research Triangle Park
Altavant Sciences Inc.

Altavant is a clinical stage biopharmaceutical company developing therapies for rare respiratory diseases. Altavant's initial therapeutic focus is in pulmonary arterial hypertension (PAH).

Cary
Alterna Therapeutics Inc.

Alterna Therapeutics is developing first-in-class small molecules targeting the SHIP enzyme. Alterna is exploring its lead compounds in the areas of obesity, diabetes, bone marrow transplant and post-myeloblative therapy, cancer and Alzheimer's disease.

Durham
Altis BioSystems Inc.

Altis Biosystems has developed a stem cell technology that recreates the human intestinal epithelium in a 2D or 3D layer of intestinal stem and differentiated cells, which can be used for compound screening, microbiome research and disease modeling.

Chapel Hill
AMO Pharma Ltd.

AMO Pharma is developing new treatments for serious and debilitating diseases including rare genetic disorders.

Durham
AnelleO

AnelleO is developing a 3D-printed intravaginal ring that can be used for treating infertility and a wide range of other women's health conditions.

Chapel Hill
Aniluxx Biotechnology Inc.

Aniluxx Biotechnology translates human therapies to dogs, cats and horses to treat itching and pain.

Raleigh
Apeirolux Pharmaceutical Inc.

Apeirolux Pharmaceutical is developing a tumor-cell selective topical skin cream for the treatment of skin cancer.

Fuquay Varina
Appealing Products Inc.

Appealing Products develops products for forensics and personal protection from toxic materials such as inorganics, gases and poisons in foods, animal feeds and liquids.

Raleigh
Applied Catheter Technologies Inc.

Applied Catheter Technologies develops drug-coated medical devices that inhibit scar formation. The company's first products under development are catheters for male urethral stricture and devices that inhibit abdominal adhesions.

Winston-Salem
Applied LifeSciences & Systems Poultry Inc.

Applied LifeSciences & Systems Poultry develops automated bio-system solutions for detecting, targeting and delivering vaccines to poultry. ALS-S technology aims to reduce the need for antibiotics by improving vaccination delivery.

Morrisville
Arbiom Inc.

Arbiom develops technologies that convert residues from agriculture and forestry into a high-protein ingredient for aquaculture and animal feed. The Raleigh office is Arbiom's application center.

Durham
Arcato Laboratories Inc.

Arcato Laboratories develops specialty oral healthcare products including treatment for pain and discomfort from orthodontic appliances and post-surgical tooth extraction.

Greenville
Ardeal Pharma Inc.

Ardeal Pharma is a virtual pharma company developing patented stabilized sulforaphane for the dermal pharmaceutical and cosmetic markets.

Brevard
Ardeal Research Institute

Ardeal Research Institute is a non-profit organization that develops drug discovery capabilities of the natural resources in Western North Carolina. The Institute has collaboration agreements in place with Brevard College and the N.C. Arboretum.

Brevard
Array BioPharma Inc.

Array BioPharma discovers, develops and commercializes targeted, small-molecule drugs to treat cancer.

Morrisville
Arrevus Inc.

Arrevus is developing novel therapeutics for unmet medical needs in areas with high treatment failure rates, including infectious disease, brain cancer and breast cancer.

Raleigh
Arrivo BioVentures LLC

Arrivo BioVentures accelerates biologics and small molecules from IND/phase one through proof-of-concept, with biologics in development for dermatologic conditions and hearing loss.

Morrisville
Artizan Biosciences Inc.

Artizan is developing a platform for identifying and targeting pathogenic intestinal bacteria, with a focus on inflammatory bowel disease and potential applications in autoimmune diseases, obesity, skin, lung and central nervous system diseases.

Durham
Aruna Bio

Aruna Bio develops neural exosomes for the treatment of neurodegenerative diseases.

Raleigh
Ascent Bio-Nano Technologies Inc.

Ascent Bio-Nano Technologies develops cell and particle separation research tools and medical devices.

Research Triangle Park
AskBio

Asklepios BioPharmaceutical (AskBio) uses adeno-associated virus (AAV) technology to develop and manufacture gene therapies for rare diseases and other genetic disorders.

Research Triangle Park
Atlantic Medical Inc.

Atlantic Medical develops nutraceutical products and devices to address ocular diseases.

Wrightsville Beach
Atlas Regeneration Inc.

Atlas Regeneration develops bioinformatics platforms for drug discovery related to regenerative medicine and stem cell research. Atlas Regeneration also screens drugs in silico for drug repositioning.

Winston-Salem
Atom Bioworks Inc.

Atom Bioworks has developed a Pattern-recognition Enabled Sensing and Therapeutics (PEST) platform to identify viruses and possible treatments.

Cary
Atox Bio Inc.

Atox Bio develops novel immunomodulators to treat critically ill patients. Therapeutic indications include necrotizing soft tissue infection and sepsis-associated acute kidney injury.

Chapel Hill
Atrium Health Division of Therapeutic Research and Development

The Division of Therapeutic Research and Development at Atrium Health conducts clinical studies, patient-focused translational research and outcomes research.

Charlotte
Attagene Inc.

Attagene has developed a pathway profiling technology to evaluate the impact of pharmaceuticals and environmental chemicals on over 100 transcription factors and 48 nuclear receptors.

Morrisville
Auration Biotech Inc.

Auration Biotech is developing novel therapeutics for ear, nose and throat diseases.

Chapel Hill
Aurobindo Pharma USA Inc.

Aurobindo Pharma is a generic drug manufacturer. Aurobindo develops inhalation and dermatological products from the company's U.S. research and development headquarters in North Carolina.

Durham
Avertica Inc.

Avertica develops compounds and polymers for electronic device applications, including the development of biomimetic and bio-based electronic materials.

Research Triangle Park
Avior Inc.

Avior is developing a nanoparticle-based drug delivery technology to deliver lipophilic drugs with high bioavailability. It is testing its technology using a molecule for the treatment of pruritus in chronic kidney disease.

Durham
Avolynt Inc.

Avolynt is developing therapeutics for rare and metabolic disease. Avolynt's lead programs target Type 2 diabetes, NASH and Post Bariatric Hypoglycemia.

Research Triangle Park
Axovant Sciences Inc.

Axovant Sciences develops gene therapies to treat neurologic conditions.

Durham
Balanced pHarma Inc.

Balanced pHarma is developing a pH-balanced dental anesthetic drug.

Cornelius
Ballek Biologics LLC

Ballek Biologics is developing a therapeutic to reverse opioid overdose.

Raleigh
Banner Life Sciences LLC

Banner Life Sciences develops formulation technologies (gelcaps, tablets and sterile injectables) and licenses and markets prescription, over-the-counter and nutritional products.

High Point
BASF Agricultural Solutions

BASF's Agricultural Solutions division conducts seeds, traits and plant biotechnology research with a focus on yield and quality traits in major crops. Its RTP campus also houses a bee care center.

Research Triangle Park
Bavarian Nordic Inc.

Bavarian Nordic develops, manufactures and commercializes cancer immunotherapies and vaccines for infectious diseases.

Morrisville
Bayer Environmental Science

Bayer Environmental Science, a unit of Bayer CropScience, develops and markets pest-, weed- and disease-control products for non-crop situations. This facility supports development, testing and training for its consumer and professional products.

Clayton
BD Technologies and Innovation

BD Technologies and Innovation develops technologies for parenteral drug delivery, advanced diagnostics, smart medical devices and genomic research and supports external innovation. The RTP site is BD's corporate technology R&D and innovation center.

Research Triangle Park
Bedrock Therapeutics Inc.

Bedrock Therapeutics is developing treatments for hemophilia and ocular disorders, as well as AAV platform technologies for gene therapy.

Chapel Hill
BENANOVA Inc.

BENANOVA develops antimicrobial nanotechnology products for the disinfectant, cosmetic and agricultural industries.

Raleigh
Bent Creek Institute Inc.

Bent Creek Institute is a 501(c)3 non-profit botanical research and economic development organization serving primarily North Carolina-based natural products companies seeking to innovate botanical wellness solutions.

Asheville
BioAesthetics Corporation

BioAesthetics Corporation is developing a nipple areolar complex graft that allows the patients' cells to grow into the graft for use in breast reconstruction.

Research Triangle Park
BioCryst Pharmaceuticals Inc.

BioCryst Pharmaceuticals designs and develops novel, small-molecule oral drugs that block key enzymes to treat rare diseases. The Durham location houses BioCryst's clinical, regulatory and executive teams.

Durham
BioCytics Inc.

BioCytics researches and develops personalized cellular immunotherapy cancer therapies with the latest technology and equipment. BioCytics also offers contract R&D and is incubated within the Carolina BioOncology Institute.

Huntersville
BioDelivery Sciences International Inc.

BioDelivery Sciences is a specialty pharmaceutical company with a focus in the areas of pain management and addiction. The company's lead products utilize a buccal film delivery system.

Raleigh
Biofluidica Inc.

Biofluidica is developing novel instrumentation for the isolation and analysis of circulating biomarkers, including circulating tumor cells, in cancer patients.

Research Triangle Park
BioIVT

BioIVT provides biological specimens, specializing in control and disease state human and animal tissues. This site develops and commercializes cell-based drug toxicity-testing products for pharmaceutical development, based on hepatocyte technologies.

Durham
BioKier Inc.

BioKier develops proprietary adjuvant treatments for diabetes and related disorders. BioKier has identified a therapeutic opportunity based on gastric bypass surgery and is developing a novel treatment for diabetes.

Chapel Hill
BioMarck Pharmaceuticals Ltd.

BioMarck develops drugs to treat pulmonary diseases and disorders, such as chronic obstructive pulmonary disease, ARDS, cystic fibrosis and lung cancer.

Durham
bioMASON Inc.

bioMASON develops cement by using microorganisms fed an aqueous solution, which harden to ASTM specification in ambient temperatures.

Research Triangle Park
BioMedInnovations LLC

BioMedInnovations (BMI) makes precision air and fluid flow devices, including products for lung ventilators and ex-vivo organ and tissue perfusion.

Denver
BioMedomics Inc.

BioMedomics develops point-of-care (POC) diagnostics in hematology oncology, virology, women’s health and dermatology.

Durham
BioResource International Inc.

BioResource International (BRI) designs, develops and manufactures unique enzymes that help poultry and swine producers optimize animal nutrition and gut health.

Durham
Biorg Inc.

Biorg is developing and commercializing organoid technology for use in life science applications such as diagnostics, drug screenings and toxicology.

Winston-Salem
BioRxn LLC

BioRxn develops NMR-based metabolomic technology, including bioreactor and artificial liver systems, for non-invasive monitoring of metabolic biomarkers. BioRxn also provides conventional metabolomic services.

Chapel Hill
BioSkryb Corp.

BioSkryb's SkrybAmp technology is a new DNA amplification technology powered by Primary Template Directed Amplification (PTA).

Durham
Biotality

Biotality develops biological and natural products for crop protection. Its first product is a proprietary organism that overproduces a fungicidal exudate, with applications in the seed protectant and post-harvest markets.

Research Triangle Park
Biotech Restorations LLC

Biotech Restorations formulates bioremediation products for the cleanup of petroleum and chlorinated hydrocarbons including gasoline and diesel, organochloride pesticides, PCBs and volatile organic chemicals in soil, sediment and groundwater.

Denver
Bioventus LLC

Bioventus develops and markets orthobiologic solutions for musculoskeletal healing and regeneration. These include products for bone healing, bone graft and knee osteoarthritis.

Durham
BioZyme Inc.

BioZyme develops and sells substrates for metalloproteinases (MMPs and ADAMs) which can be used in enzyme assays and other diagnostic tests.

Apex
Blue Ridge Institute for Medical Research

Blue Ridge Institute for Medical Research (BRIMR) researches small-molecule inhibitors of protein kinases and targeted cancer therapies. BRIMR also generates an annual ranking of NIH funding for U.S. medical schools and their departments.

Horse Shoe
Boragen Inc.

Boragen is developing a synthetic chemistry platform that leverages the unique characteristics of boron to address life science needs in crop protection and animal health.

Research Triangle Park
Brain Neurotherapy Bio Inc.

Brain Neurotherapy Bio is developing delivery technologies for viral vector-based gene therapies to treat adult and pediatric central nervous system disorders.

Research Triangle Park
BreStem Therapeutics Inc.

BreStem Therapeutics is developing a stem cell therapy to treat pulmonary fibrosis.

Raleigh
Brighton Development LLC

Brighton Development develops sterilizing technologies and antimicrobial medical plastics.

Cary
Brii Biosciences

Brii Biosciences combines partnerships, research and development, and digital and data insight to improve access to medicines for patients in China.

Durham
Bryn Pharma LLC

Bryn Pharma is developing a nasal solution for the administration of emergency epinephrine for the treatment of anaphylaxis.

Raleigh
Cancer Advances Inc.

Cancer Advances, a subsidiary of Cato Bioventures, develops immunomodulator therapeutics to treat gastrointestinal cancers.

Durham
Capture Pharmaceuticals Inc.

Capture Pharmaceuticals develops oral treatments for removing toxic or radioactive metals in contaminated individuals.

Chapel Hill
CardioEphEx LLC

CardioEphEx develops therapeutics for cardiovascular disease and heart failure. The company's research focuses on cardioprotection by targeting the Ephrin/Eph receptor signaling pathway in the heart.

Bahama
CardioPharma Inc.

CardioPharma develops combinatorial products to treat cardiovascular disease.

Wilmington
Catalyst Medicine LLC

Catalyst Medicine designs, develops and commercializes Class 1 and Class 2 medical devices in the areas of neurology, orthopedics, cardiology and plastic surgery.

Durham

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